Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes
(2018)
Journal Article
Almulathanon, A. A., Ranucci, E., Ferruti, P., Garnett, M. C., & Bosquillon, C. (2018). Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes. Pharmaceutical Research, 35(4), doi:10.1007/s11095-017-2328-7. ISSN 0724-8741
Purpose: This study aimed to further explore the mechanisms behind the ability of certain linear polyamidoamines (PAAs) to transfect cells with minimal cytotoxicity. Methods: The transfection efficiency of DNA complexed with a PAA of a molecular we... Read More