Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes (2018)
Journal Article
Almulathanon, A. A., Ranucci, E., Ferruti, P., Garnett, M. C., & Bosquillon, C. (2018). Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes. Pharmaceutical Research, 35(4), doi:10.1007/s11095-017-2328-7. ISSN 0724-8741

Purpose: This study aimed to further explore the mechanisms behind the ability of certain linear polyamidoamines (PAAs) to transfect cells with minimal cytotoxicity. Methods: The transfection efficiency of DNA complexed with a PAA of a molecular we... Read More

IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients (2017)
Journal Article
Ahmad, N., Ammar, A., Storr, S. J., Green, A. R., Rakha, E., Ellis, I., & Martin, S. G. (2018). IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients. Cancer Immunology, Immunotherapy, 67(4), doi:10.1007/s00262-017-2106-8

Macrophage-associated cytokines play an important role in cancer metastasis however the functions of Interleukins (IL) 6 and 10 in breast cancer (BC) progression and metastasis are not clear. In this study the roles of IL-6/IL-10 in regulating vascul... Read More

How integrated are neurology and palliative care services? Results of a multicentre mapping exercise (2016)
Journal Article
van Vliet, L. M., Gao, W., DiFrancesco, D., Crosby, V., Wilcock, A., Byrne, A., …Higginson, I. J. (in press). How integrated are neurology and palliative care services? Results of a multicentre mapping exercise. BMC Neurology, 16, doi:10.1186/s12883-016-0583-6. ISSN 1471-2377

Background: Patients affected by progressive long-term neurological conditions might benefit from specialist palliative care involvement. However, little is known on how neurology and specialist palliative care services interact. This study aimed to... Read More