Next-generation RNA-Sequencing of serum small extracellular vesicles discovers potential diagnostic biomarkers for dementia with Lewy bodies
(2020)
Journal Article
Rajkumar, A. P., Hye, A., Lange, J., Rashid Manesh, Y., Ballard, C., Fladby, T., & Aarsland, D. (2021). Next-generation RNA-Sequencing of serum small extracellular vesicles discovers potential diagnostic biomarkers for dementia with Lewy bodies. American Journal of Geriatric Psychiatry, 29(6), 573-584. https://doi.org/10.1016/j.jagp.2020.10.012
Objectives: There is an urgent clinical need for identifying blood-based diagnostic biomarkers for Dementia with Lewy Bodies (DLB). Transcriptomic studies have reported unique RNA changes in post-mortem DLB brains. Small extracellular vesicles (SEV)... Read More about Next-generation RNA-Sequencing of serum small extracellular vesicles discovers potential diagnostic biomarkers for dementia with Lewy bodies.