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How is a specialist depression service effective for persistent moderate to severe depressive disorder?: a qualitative study of service user experience (2018)
Journal Article
Thomson, L., Barker, M., Kaylor-Hughes, C., Garland, A., Ramana, R., Morriss, R., …Simpson, S. (2018). How is a specialist depression service effective for persistent moderate to severe depressive disorder?: a qualitative study of service user experience. BMC Psychiatry, 18(1), https://doi.org/10.1186/s12888-018-1708-9

Background. A specialist depression service (SDS) offering collaborative pharmacological and cognitive behaviour therapy treatment for persistent depressive disorder showed effectiveness against depression symptoms versus usual community based multid... Read More about How is a specialist depression service effective for persistent moderate to severe depressive disorder?: a qualitative study of service user experience.

Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling (2017)
Journal Article
Guo, B., Kaylor-Hughes, C., Garland, A., Nixon, N., Sweeney, T., Simpson, S., …Morriss, R. (2017). Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling. Journal of Affective Disorders, 219, 1-8. https://doi.org/10.1016/j.jad.2017.05.020

Background: The Patient Health Questionnaire-9 (PHQ-9) is a widely used instrument for measuring levels of depression in patients in clinical practice and academic research; its factor structure has been investigated in various samples, with limited... Read More about Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling.

Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial (2016)
Journal Article
Morriss, R., Garland, A., Nixon, N., Guo, B., James, M., Kaylor-Hughes, C., …Dalgleish, T. (2016). Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial. Lancet Psychiatry, 3(9), 821-831. https://doi.org/10.1016/s2215-0366%2816%2930143-2

Background: Persistent moderate or severe unipolar depression is common and expensive to treat. Clinical guidelines recommend combined pharmacotherapy and psychotherapy. Such treatments can take up to 1 year to show an effect, but no trials of suitab... Read More about Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial.

Clinical effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: the CoBalT randomised controlled trial (2014)
Journal Article
Wiles, N., Thomas, L., Abel, A., Barnes, M., Carroll, F., Ridgway, N., …Lewis, G. (2014). Clinical effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: the CoBalT randomised controlled trial. Health Technology Assessment, 18(31), https://doi.org/10.3310/hta18310

Cost-effectiveness of cognitive–behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: economic evaluation of the CoBalT Trial (2014)
Journal Article
Hollinghurst, S., Carroll, F. E., Abel, A., Campbell, J., Garland, A., Jerrom, B., …Wiles, N. (2014). Cost-effectiveness of cognitive–behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: economic evaluation of the CoBalT Trial. British Journal of Psychiatry, 204(1), 69-76. https://doi.org/10.1192/bjp.bp.112.125286