Research Repository

See what's under the surface


Position matching between the visual fields in strabismus (2018)
Journal Article
Hussain, Z., Astle, A. T., Webb, B. S., & McGraw, P. V. (2018). Position matching between the visual fields in strabismus. Journal of Vision, 18(1), doi:10.1167/18.1.9. ISSN 1534-7362

The misalignment of visual input in strabismus disrupts positional judgments.We measured positional accuracy in the extrafoveal visual field (18–78 eccentricity) of a large group of strabismic subjects and a normal control group to identify positiona... Read More

Spatial interpolation enables normative data comparison in gaze-contingent microperimetry (2016)
Journal Article
Denniss, J., & Astle, A. T. (2016). Spatial interpolation enables normative data comparison in gaze-contingent microperimetry. Investigative Ophthalmology & Visual Science, 57(13), doi:10.1167/iovs.16-20222. ISSN 0146-0404

Purpose: To demonstrate methods that enable visual field sensitivities to be compared with normative data without restriction to a fixed test pattern. Methods: Healthy participants (n = 60, age 19–50) undertook microperimetry (MAIA-2) using 237 sp... Read More

The consequences of strabismus and the benefits of adult strabismus surgery (2016)
Journal Article
Astle, A. T., Foulsham, T., & McGraw, P. V. (2016). The consequences of strabismus and the benefits of adult strabismus surgery. Optometry in Practice, 17(3), ISSN 1467-9051

Strabismus has a negative impact on patients’ lives regardless of their age. Factors such as self-esteem, relationships with others, education and the ability to find employment may all be negatively affected by strabismus. It is possible to correct... Read More

Central visual field sensitivity data from microperimetry with spatially dense sampling (2016)
Journal Article
Astle, A. T., Ali, I., & Denniss, J. (in press). Central visual field sensitivity data from microperimetry with spatially dense sampling. Data in Brief, doi:10.1016/j.dib.2016.07.061. ISSN 2352-3409

Microperimetry, also referred to as fundus perimetry or fundus-driven perimetry, enables simultaneous acquisition of visual sensitivity and eye movement data. We present sensitivity data collected from 60 participants with normal vision using gaze-co... Read More

Is the frequency of adult strabismus surgery increasing? (2016)
Journal Article
Astle, A. T., Foulsham, T., Foss, A. J., & McGraw, P. V. (in press). Is the frequency of adult strabismus surgery increasing?. Ophthalmic and Physiological Optics, 36(4), doi:10.1111/opo.12306. ISSN 0275-5408

Purpose In recent years there has been an increase in evidence for the functional and psychosocial benefits of correcting strabismus/heterotropia in adults. This study aimed to establish whether there has been an associated change in the frequency o... Read More

Central perimetric sensitivity estimates are directly influenced by the fixation target (2016)
Journal Article
Denniss, J., & Astle, A. T. (in press). Central perimetric sensitivity estimates are directly influenced by the fixation target. Ophthalmic and Physiological Optics, 36(4), doi:10.1111/opo.12304/abstract. ISSN 0275-5408

Purpose: Perimetry is increasingly being used to measure sensitivity at central visual field locations. For many tasks, the central (0°, 0°) location is functionally the most important, however threshold estimates at this location may be affected by... Read More

Task-specific transfer of perceptual learning across sensory modalities (2016)
Journal Article
McGovern, D. P., Astle, A. T., Clavin, S. L., & Newell, F. N. (in press). Task-specific transfer of perceptual learning across sensory modalities. Current Biology, 26(1), doi:10.1016/j.cub.2015.11.048. ISSN 0960-9822

It is now widely accepted that primary cortical areas of the brain that were once thought to be sensory-specific undergo significant functional reorganisation following sensory deprivation. For instance, loss of vision or audition leads to the brain... Read More

The effect of normal aging and age-related macular degeneration on perceptual learning (2015)
Journal Article
Astle, A. T., Blighe, A., Webb, B. S., & McGraw, P. V. (2015). The effect of normal aging and age-related macular degeneration on perceptual learning. Journal of Vision, 15(10), doi:10.1167/15.10.16. ISSN 1534-7362

We investigated whether perceptual learning could be used to improve peripheral word identification speed. The relationship between the magnitude of learning and age was established in normal participants to determine whether perceptual learning effe... Read More

Characterizing the role of disparity information in alleviating visual crowding (2014)
Journal Article
Astle, A. T., McGovern, D. P., & McGraw, P. V. (2014). Characterizing the role of disparity information in alleviating visual crowding. Journal of Vision, 14(6), doi:10.1167/14.6.8. ISSN 1534-7362

The ability to identify a target is reduced by the presence of nearby objects, a phenomenon known as visual crowding. The extent to which crowding impairs our perception is generally governed by the degree of similarity between a target stimulus and... Read More

The challenges of developing a contrast-based video game for treatment of amblyopia (2014)
Journal Article
Hussain, Z., Astle, A. T., Webb, B. S., & McGraw, P. V. (2014). The challenges of developing a contrast-based video game for treatment of amblyopia. Frontiers in Psychology, 5, doi:10.3389/fpsyg.2014.01210. ISSN 1664-1078

Perceptual learning of visual tasks is emerging as a promising treatment for amblyopia, a developmental disorder of vision characterized by poor monocular visual acuity. The tasks tested thus far span the gamut from basic psychophysical discriminatio... Read More

The effect of aging on crowded letter recognition in the peripheral visual field (2014)
Journal Article
Astle, A. T., Blighe, A. J., Webb, B. S., & McGraw, P. V. (2014). The effect of aging on crowded letter recognition in the peripheral visual field. Investigative Ophthalmology & Visual Science, 55(8), doi:10.1167/iovs.14-14181. ISSN 0146-0404

Purpose.: Crowding describes the increased difficulty in identifying a target object when it is surrounded by nearby objects (flankers). A recent study investigated the effect of age on visual crowding and found equivocal results: Although crowded vi... Read More

A Weber-like law for perceptual learning (2013)
Journal Article
Astle, A. T., Li, R. W., Webb, B. S., Levi, D. M., & McGraw, P. V. (2013). A Weber-like law for perceptual learning. Scientific Reports, 3, doi:10.1038/srep01158. ISSN 2045-2322

What determines how much an organism can learn? One possibility is that the neural factors that limit sensory performance prior to learning, place an upper limit on the amount of learning that can take place. We tested this idea by comparing learning... Read More

Perceptual learning reduces crowding in amblyopia and in the normal periphery (2012)
Journal Article
Hussain, Z., Webb, B. S., Astle, A. T., & McGraw, P. V. (2012). Perceptual learning reduces crowding in amblyopia and in the normal periphery. Journal of Neuroscience, 32(2), doi:10.1523/JNEUROSCI.3845-11.2012. ISSN 1529-2401

Amblyopia is a developmental visual disorder of cortical origin, characterized by crowding and poor acuity in central vision of the affected eye. Crowding refers to the adverse effects of surrounding items on object identification, common only in nor... Read More

The pattern of learned visual improvements in adult amblyopia (2011)
Journal Article
Astle, A. T., Webb, B. S., & McGraw, P. V. (2011). The pattern of learned visual improvements in adult amblyopia. Investigative Ophthalmology & Visual Science, 52(10), doi:10.1167/iovs.11-7584. ISSN 0146-0404

Purpose. Although amblyopia is diagnosed in terms of a monocular letter acuity loss, individuals typically present with deficits on a wide range of spatial tasks. Many of these deficits can be collapsed along two basic visual dimensions (visual acuit... Read More

Can human amblyopia be treated in adulthood? (2011)
Journal Article
Astle, A. T., McGraw, P. V., & Webb, B. S. (in press). Can human amblyopia be treated in adulthood?. Strabismus, 19(3), doi:10.3109/09273972.2011.600420. ISSN 0927-3972

Amblyopia is a common visual disorder that results in a spatial acuity deficit in the affected eye. Orthodox treatment is to occlude the unaffected eye for lengthy periods, largely determined by the severity of the visual deficit at diagnosis. Althou... Read More

Spatial frequency discrimination learning in normal and developmentally impaired human vision (2010)
Journal Article
Astle, A. T., Webb, B. S., & McGraw, P. V. (2010). Spatial frequency discrimination learning in normal and developmentally impaired human vision. Vision Research, 50(23), doi:10.1016/j.visres.2010.09.004. ISSN 0042-6989

Perceptual learning effects demonstrate that the adult visual system retains neural plasticity. If perceptual learning holds any value as a treatment tool for amblyopia, trained improvements in performance must generalise. Here we investigate whether... Read More