All Outputs (11)

Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis (2019)
Journal Article
Webb, K., Fogarty, A., Barrett, D. A., Nash, E. F., Whitehouse, J. L., Smyth, A. R., …Cámara, M. (2019). Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis. Journal of Medical Microbiology, 68(12), 1823-1828. https://doi.org/10.1099/jmm.0.001099

Introduction : Pseudomonas aeruginosa is an important respiratory pathogen in cystic fibrosis (CF), which is associated with an accelerated decline in lung function, frequent pulmonary exacerbations and increased mortality. P. aeruginosa produces in... Read More about Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.

Rojiroti microfinance and child nutrition: a cluster randomised trial (2019)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A., Allen, S., …Smyth, A. R. (2020). Rojiroti microfinance and child nutrition: a cluster randomised trial. Archives of Disease in Childhood, 105(3), 229-235. https://doi.org/10.1136/archdischild-2018-316471

Objective To determine whether Rojiroti microfinance, for poor Indian women, improves child nutrition. Design Cluster randomised trial. Setting Tolas (village communities) in Bihar State. Participants Women and children under 5 years. Int... Read More about Rojiroti microfinance and child nutrition: a cluster randomised trial.

The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data (2018)
Journal Article
Rodríguez-Calá, F., Suárez-Medina, R., Josefina Venero-Fernández, S., Smyth, A., Carr, S. B., & Fogarty, A. W. (2019). The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data. Journal of Cystic Fibrosis, 18(4), 522-524. https://doi.org/10.1016/j.jcf.2018.10.007

Background: We aimed to establish a national cystic fibrosis (CF) registry for Cuba, a developing country. Methods: Regional centres that deliver care for all CF patients provided information for a national database. Findings: The prevalence of CF... Read More about The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data.

Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis (2017)
Journal Article
Hurley, M., Fogarty, A. W., McKeever, T. M., Goss, C., Rosenfeld, M., & Smyth, A. R. (in press). Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis. Annals of the American Thoracic Society, https://doi.org/10.1513/AnnalsATS.201705-376OC

Rationale: Consensus is lacking regarding anti-staphylococcal antibiotic prophylaxis use for young children with cystic fibrosis. Prophylaxis is recommended in the UK, but recommended against in the US. Objectives: To test the hypothesis that anti-... Read More about Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis.

Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis (2017)
Journal Article
Barr, H. L., Cámara, M., Barrett, D., Williams, P., Forrester, D., Smyth, A., …Fogarty, A. W. (in press). Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis. ERJ Open Research, 3(3), https://doi.org/10.1183/23120541.00057-2017

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study (2016)
Journal Article
Barr, H. L., Halliday, N., Barrett, D. A., Williams, P., Forrester, D. L., Peckham, D., …Fogarty, A. W. (2017). Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16(2), 230-238. https://doi.org/10.1016/j.jcf.2016.10.005

Background Pulmonary P. aeruginosa infection is associated with poor outcomes in cystic fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to expectorate sputum. Specific P. aeruginosa 2-alkyl-4-quinolones are det... Read More about Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study.

Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis (2015)
Journal Article
Forrester, D. L., Knox, A. J., Smyth, A. R., Barr, H. L., Simms, R., Pacey, S. J., …Fogarty, A. W. (2016). Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis. Pediatric Pulmonology, 51(3), 253-257. https://doi.org/10.1002/ppul.23370

Rationale: Pulmonary infection and malnutrition in cystic fibrosis are associated with decreased survival. Glutamine has a possible anti-microbial effect, with a specific impact against Pseudomonas aeruginosa. We aimed to test the hypothesis that ora... Read More about Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis.

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis (2015)
Journal Article
Barr, H. L., Halliday, N., Cámara, M., Barrett, D. A., Williams, P., Forrester, D. L., …Fogarty, A. W. (2015). Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis. European Respiratory Journal, 46(4), 1046-1054. https://doi.org/10.1183/09031936.00225214

Copyright © ERS 2015. Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for... Read More about Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis.

Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial (2014)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A. W., Allen, S., …Smyth, A. R. (2014). Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial. Trials, 15, Article 298. https://doi.org/10.1186/1745-6215-15-298

Background: The United Nations Millennium Development Goals include targets for the health of children under five years old. Poor health is linked to poverty and microfinance initiatives are economic interventions that may improve health by breaking... Read More about Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial.

Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study (2014)
Journal Article
Hurley, M., McKeever, T. M., Prayle, A. P., Smyth, A. R., & Fogarty, A. W. (2014). Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study. Journal of Cystic Fibrosis, 13(4), https://doi.org/10.1016/j.jcf.2013.12.002

Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. Method: Death registration data analysis (US, England & Wa... Read More about Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study.

Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis
Other
Hurley, M., Smyth, A. R., Fogarty, A. W., McKeever, T. M., Rosenfeld, M., & Goss, C. (2016). Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis