Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells

Quilles Junior, Jos� C.; Bradshaw, Tracey D; Turyanska, Lyudmila; Carlos, Fernanda dos Reis Rocho; Montanari, A.; Leit�o, Andrei; Mignone, Viviane W.; Arruda, Maria Augusta; Turyanska, Lyudmila; Bradshaw, Tracey D.

doi:10.1039/c9ra07161j

All Outputs (1)

Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells (2019)
Journal Article
Quilles Junior, J. C., Bradshaw, T. D., Turyanska, L., Carlos, F. D. R. R., Montanari, A., Leitão, A., …Bradshaw, T. D. (2019). Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells. RSC Advances, 9(63), 36699-36706. https://doi.org/10.1039/c9ra07161j

Cysteine proteases play a key role in tumorigenesis causing protein degradation and promoting invasive tumour growth. Cathepsin L is overexpressed in cancer cells and could provide a specific target for delivery of anticancer agents. We encapsulated... Read More about Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells.