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All Outputs (166)

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections. F1000Research, 10, 1-39. https://doi.org/10.12688/f1000research.51270.2

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections.

Rehabilitation potential in older people living with frailty: a systematic mapping review (2021)
Journal Article
Cowley, A., Goldberg, S. E., Gordon, A. L., & Logan, P. A. (2021). Rehabilitation potential in older people living with frailty: a systematic mapping review. BMC Geriatrics, 21(1), Article 533. https://doi.org/10.1186/s12877-021-02498-y

Background: Following periods of acute ill-health and injury, older people are frequently assessed and provided with rehabilitation services. Healthcare practitioners are required to make nuanced decisions about which patients are likely to benefit f... Read More about Rehabilitation potential in older people living with frailty: a systematic mapping review.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations] (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations]. F1000Research, 10, 1-34. https://doi.org/10.12688/f1000research.51270.1

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations].

Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals (2021)
Journal Article
Schlögl, M., Singler, K., Martinez-Velilla, N., Jan, S., Bischoff-Ferrari, H. A., Roller-Wirnsberger, R. E., …Gordon, A. L. (2021). Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals. European Geriatric Medicine, 12(6), 1181-1190. https://doi.org/10.1007/s41999-021-00532-1

Purpose The aims of this study were to describe communication experiences while wearing a mask during COVID-19 pandemic in 2020, in order to identify possible mask-related barriers to COVID-19-adapted communications and to investigate whether the AB... Read More about Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals.

Research into ageing and frailty (2021)
Journal Article
Gordon, A. L., Witham, M. D., Henderson, E. J., Harwood, R. H., & Masud, T. (2021). Research into ageing and frailty. Future Healthcare Journal, 8(2), e237-e242. https://doi.org/10.7861/fhj.2021-0088

Research into ageing covers opportunities and challenges posed by an older population, and research to understand the ageing processes across the lifespan. The evidence base for Comprehensive Geriatric Assessment (CGA) is well established and efforts... Read More about Research into ageing and frailty.

FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study (2021)
Working Paper
Urwin, S. G., Lendrem, B. C., Suklan, J., Green, K., Graziadio, S., Buckle, P., …Allen, A. J. FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study

Background: Point-of-care (POC) tests for COVID-19 could relieve pressure on isolation resource, support infection prevention and control, and help commence more timely and appropriate treatment. We aimed to undertake a systematic review and pooled d... Read More about FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study.

HEARTS, minds and souls—it is time for geriatricians to bring more to continence management (2021)
Journal Article
Schlögl, M., & Gordon, A. (2021). HEARTS, minds and souls—it is time for geriatricians to bring more to continence management. Age and Ageing, 50(5), 1508-1511. https://doi.org/10.1093/ageing/afab088

Urinary incontinence (UI), the involuntary loss of urine, is a common health condition that may decrease the quality of life and which increases in incidence and prevalence with age. Recent epidemiologic data suggest an overall prevalence of 38% in w... Read More about HEARTS, minds and souls—it is time for geriatricians to bring more to continence management.

Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study (2021)
Journal Article
Aloraibi, S., Gladman, J., Godfrey, D., Booth, V., Robinson, K., Lunt, E., …Gordon, A. L. (2021). Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study. BMC Geriatrics, 21(1), Article 332. https://doi.org/10.1186/s12877-021-02265-z

Background: Older people who are non-weight-bearing after a lower limb fracture are at risk of poor outcomes but there are no clinical guidelines for this group of patients. Given the paucity of the research evidence base, we conducted a consensus ex... Read More about Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study.

Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review (2021)
Journal Article
Aloraibi, S., Booth, V., Robinson, K., Lunt, E. K., Godfrey, D., Caswell, A., …Gladman, J. (2021). Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review. Age and Ageing, 50(4), 1129–1136. https://doi.org/10.1093/ageing/afab071

Background Patients with lower limb fractures who are non-weight bearing are at risk of the complications of the associated immobility and disability, particularly people with frailty, but there is lack of clarity about what constitutes optimal ca... Read More about Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review.

COVID-19 point-of-care testing in care homes: what are the lessons for policy and practice? (2021)
Journal Article
Buckle, P., Micocci, M., Tulloch, J., Kierkegaard, P., Parvulescu, P., Thompson, C., …Gordon, A. L. (2021). COVID-19 point-of-care testing in care homes: what are the lessons for policy and practice?. Age and Ageing, 50(5), 1442-1444. https://doi.org/10.1093/ageing/afab101

COVID-19 has devastated care homes. Point of care tests (POCTs), mainly using Lateral Flow Devices (LFDs), have been deployed hurriedly without much consideration of their usability or impact on care workflow. Even after the pandemic POCTs, particula... Read More about COVID-19 point-of-care testing in care homes: what are the lessons for policy and practice?.

Is point-of-care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a point-of-care polymerase chain reaction test for SARS-CoV-2 (2021)
Journal Article
Micocci, M., Gordon, A. L., Kelly Seo, M., Joy Allen, A., Davies, K., Hayward, G., …Buckle, P. (2021). Is point-of-care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a point-of-care polymerase chain reaction test for SARS-CoV-2. Age and Ageing, 50(5), 1464-1472. https://doi.org/10.1093/ageing/afab072

Introduction: Reliable rapid testing for COVID-19 is needed in care homes to reduce the risk of outbreaks and enable timely care. This study aimed to examine the usability and test performance of a point of care polymerase chain reaction (PCR) test... Read More about Is point-of-care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a point-of-care polymerase chain reaction test for SARS-CoV-2.

Exploring rehabilitation potential in older people living with frailty: a qualitative focus group study (2021)
Journal Article
Cowley, A., Goldberg, S. E., Gordon, A. L., Kerr, M., & Logan, P. (2021). Exploring rehabilitation potential in older people living with frailty: a qualitative focus group study. BMC Geriatrics, 21(1), 1-11. https://doi.org/10.1186/s12877-021-02107-y

Background: Rehabilitation interventions are frequently cited as key in supporting frail older people’s recovery following periods of decompensation and acute ill-health. Clinicians are required to make decisions about a patient’s potential to respon... Read More about Exploring rehabilitation potential in older people living with frailty: a qualitative focus group study.

How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation (2021)
Journal Article
Devi, R., Chadborn, N. H., Meyer, J., Banerjee, J., Goodman, C., Dening, T., …Gordon, A. L. (2021). How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation. Age and Ageing, 50(4), 1371-1381. https://doi.org/10.1093/ageing/afab007

Background Quality improvement collaboratives (QICs) bring together multidisciplinary teams in a structured process to improve care quality. How QICs can be used to support healthcare improvement in care homes is not fully understood. Methods A... Read More about How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation.

Care homes, their communities, and resilience in the face of the COVID-19 pandemic: interim findings from a qualitative study (2021)
Journal Article
Marshall, F., Gordon, A. L., Gladman, J. R., & Bishop, S. (2021). Care homes, their communities, and resilience in the face of the COVID-19 pandemic: interim findings from a qualitative study. BMC Geriatrics, 21, Article 102. https://doi.org/10.1186/s12877-021-02053-9

Background: From late February 2020, English care homes rapidly adapted their practices in response to the COVID-19 pandemic. In addition to accommodating new guidelines and policies, staff had to adjust to rapid reconfiguration of services external... Read More about Care homes, their communities, and resilience in the face of the COVID-19 pandemic: interim findings from a qualitative study.

Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study (2020)
Journal Article
Siraj, R., McKeever, T., Gibson, J., Gordon, A., & Bolton, C. (2021). Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study. Respiratory Medicine, 177, Article 106288. https://doi.org/10.1016/j.rmed.2020.106288

Background: Although cognitive impairment and dementia are common comorbidities in patients with chronic obstructive pulmonary disease (COPD), estimates of incidence following a diagnosis of COPD are inconclusive. Objective: To determine the incidenc... Read More about Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study.

USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER (2020)
Journal Article
Jacinto, A. F., Achterberg, W., Wachholz, P. A., Dening, T., Dening, K. H., Devi, R., …Gordon, A. (2020). USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER. Journal of Nursing Home Research, 6(109-113), https://doi.org/10.14283/jnhrs.2020.28

The Brazilian care home sector is underdeveloped, and the limited available evidence suggests that care quality falls below international standards. Development of the Brazilian care home sector could be associated with better outcomes for those rece... Read More about USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER.

August 2020 Interim EuGMS guidance to prepare European Long-Term Care Facilities for COVID-19 (2020)
Journal Article
Blain, H., Rolland, Y., Schols, J. M. G. A., Cherubini, A., Miot, S., O'Neill, D., …Benetos, A. (2020). August 2020 Interim EuGMS guidance to prepare European Long-Term Care Facilities for COVID-19. European Geriatric Medicine, 11(6), Article 899-813. https://doi.org/10.1007/s41999-020-00405-z

Purpose: The European Geriatric Medicine Society (EuGMS) is launching its second interim guidance with the aim to prevent the entrance and spread of COVID-19 into long-term care facilities (LTCFs). Methods: The EuGMS gathered experts with relevan... Read More about August 2020 Interim EuGMS guidance to prepare European Long-Term Care Facilities for COVID-19.