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All Outputs (81)

Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial (2024)
Journal Article
Howard, R., Cort, E., Rawlinson, C., Wiegand, M., Downey, A., Lawrence, V., …Gould, R. (in press). Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, https://doi.org/10.1002/alz.13766

INTRODUCTION: Trials of effectiveness of treatment options for depression in dementia are an important priority. METHODS: Randomized controlled trial to assess adapted Problem Adaptation Therapy (PATH) for depression in mild/moderate dementia caused... Read More about Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial.

Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people (2023)
Journal Article
Gordon, A. L., Martin, F., Mistry, S., Harwood, R. H., & Dhesi, J. (2023). Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people. Age and Ageing, 52(11), Article afad208. https://doi.org/10.1093/ageing/afad208

• Geriatric medicine is the largest physicianly specialty in the UK, with high levels of competition for available training posts. • Improving care of older people has been the focus of multiple national policy initiatives in the UK over the past dec... Read More about Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people.

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., …Adams, E. (2023). Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective: To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care. Design: Randomised controlled trial. Setting: Participant... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED) (2023)
Journal Article
Lorito, C. D., Van Der Wardt, V., Pollock, K., Howe, L., Booth, V., Logan, P., …Harwood, R. H. (2023). The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED). Age and Ageing, 52(8), Article afad166. https://doi.org/10.1093/ageing/afad166

Background. The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial (RCT) showed no measurable be... Read More about The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED).

Conversation Analysis Based Simulation (CABS): A method for improving communication skills training for healthcare practitioners (2023)
Journal Article
Pilnick, A., O'Brien, R., Beeke, S., Goldberg, S., Murray, M., & Harwood, R. H. (2023). Conversation Analysis Based Simulation (CABS): A method for improving communication skills training for healthcare practitioners. Health Expectations, 26(6), 2461-2474. https://doi.org/10.1111/hex.13834

Background: Actors portraying simulated patients are widely used in communication skills training in healthcare, but debates persist over the authenticity of these interactions. However, healthcare professionals value simulation‐based training becaus... Read More about Conversation Analysis Based Simulation (CABS): A method for improving communication skills training for healthcare practitioners.

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article
Ogliari, G., Ryg, J., Andersen-Ranberg, K., Scheel-Hincke, L. L., Collins, J. T., Cowley, A., …Masud, T. (2023). Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). European Geriatric Medicine, 14(5), 1111-1124. https://doi.org/10.1007/s41999-023-00835-5

Purpose To investigate the longitudinal associations between pain and depressive symptoms in adults. Methods Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study (2023)
Working Paper
Swiderski, M., Vinogradova, Y., Knaggs, R., Harman, K., Harwood, R., Prasad, V., …Gran, S. (0000). The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study

Introduction Bullous pemphigoid (BP) is a serious skin disease that results in large painful blisters developing over the body and occurs most commonly in older people (over 70 years). Despite several comorbidities such as stroke and a threefold inc... Read More about The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study.

Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study (2023)
Journal Article
Chalitsios, C. V., Baskaran, V., Harwood, R. H., Lim, W. S., & McKeever, T. M. (2023). Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study. ERJ Open Research, 9(3), Article 00328-2022. https://doi.org/10.1183/23120541.00328-2022

Background Survivors of common infections may develop cognitive impairment or dementia; however, the risk of these conditions in people hospitalised with pneumonia is not well established. Methods A matched cohort study was conducted using Hospit... Read More about Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study.

Experiences and understanding of apathy in people with neurocognitive disorders and their carers: a qualitative interview study (2023)
Journal Article
Burgon, C., Goldberg, S., van der Wardt, V., & Harwood, R. H. (2023). Experiences and understanding of apathy in people with neurocognitive disorders and their carers: a qualitative interview study. Age and Ageing, 52(3), Article afad031. https://doi.org/10.1093/ageing/afad031

Background apathy, defined as reduced goal-directed activity, interests and emotion, is highly prevalent in neurocognitive disorders (NCDs). Apathy has important consequences for the individuals who experience it and their carers, yet the lived expe... Read More about Experiences and understanding of apathy in people with neurocognitive disorders and their carers: a qualitative interview study.

The Centre for Rehabilitation and Ageing Research in Nottingham and Derby 2022. Excellence in care through world class research (2022)
Working Paper
Gladman, Logan, Gordon, Harwood, Goldberg, & Radford. (0000). The Centre for Rehabilitation and Ageing Research in Nottingham and Derby 2022. Excellence in care through world class research

It is with pleasure that we present this brochure outlining the work of the Centre for Rehabilitation and Ageing and Research (CRAR) at the University of Nottingham and its partner NHS Trusts in Nottingham, and Derby and Burton.

A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment (2022)
Journal Article
Di Lorito, C., Bosco, A., Rai, H., Craven, M., McNally, D., Todd, C., …Harwood, R. H. (2022). A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment. International Journal of Geriatric Psychiatry, 37(6), https://doi.org/10.1002/gps.5730

Objectives: Digital health interventions enable services to support people living with dementia and Mild Cognitive Impairment (MCI) remotely. This literature review gathers evidence on the effectiveness of digital health interventions on physical, co... Read More about A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment.

Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature (2021)
Journal Article
Di Lorito, C., Bosco, A., Peel, E., Hinchliff, S., Dening, T., Calasanti, T., …Harwood, R. H. (2022). Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature. Aging and Mental Health, 26(10), 1912-1921. https://doi.org/10.1080/13607863.2021.2008870

Objectives. More than 60% of people with dementia live at home, where assistance is usually provided by informal caregivers. Research on the experiences of the Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers is limited. This scoping review o... Read More about Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature.

Deconditioning in people living with dementia during the COVID-19 pandemic: qualitative study from the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) process evaluation (2021)
Journal Article
Di Lorito, C., Masud, T., Gladman, J., Godfrey, M., Dunlop, M., Bosco, A., & Harwood, R. (2021). Deconditioning in people living with dementia during the COVID-19 pandemic: qualitative study from the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) process evaluation. BMC Geriatrics, 21, 1-10. https://doi.org/10.1186/s12877-021-02451-z

Background: Restrictions introduced in response to the COVID-19 pandemic led to increased risk of deconditioning in the general population. No empirical evidence of this effect however has been gathered in people living with dementia. This study aims... Read More about Deconditioning in people living with dementia during the COVID-19 pandemic: qualitative study from the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) process evaluation.

Avoiding repair, maintaining face: Responding to hard-to-interpret talk from people living with dementia in the acute hospital (2021)
Journal Article
Pilnick, A., O'Brien, R., Beeke, S., Goldberg, S., & Harwood, R. (2021). Avoiding repair, maintaining face: Responding to hard-to-interpret talk from people living with dementia in the acute hospital. Social Science and Medicine, 282, Article 114156. https://doi.org/10.1016/j.socscimed.2021.114156

People living with dementia (PLWD) are almost always admitted to the acute hospital for reasons unrelated to their dementia, finding themselves in the unfamiliar environment of a Health Care of Older Persons acute ward. The effect of this environment... Read More about Avoiding repair, maintaining face: Responding to hard-to-interpret talk from people living with dementia in the acute hospital.

Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology (2021)
Journal Article
Burgon, C., Goldberg, S. E., Van Der Wardt, V., Brewin, C., & Harwood, R. H. (2021). Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology. Dementia and Geriatric Cognitive Disorders, 50(2), 111-123. https://doi.org/10.1159/000515678

Background: Apathy is highly prevalent in dementia and is also seen in mild cognitive impairment and the general population. Apathy contributes to failure to undertake daily activities and can lead to health problems or crises. It is therefore import... Read More about Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology.

The geriatrician’s role in end-of-life care (2020)
Journal Article
Ahmed, N., Ahmedzai, S. H., & Harwood, R. H. (2021). The geriatrician’s role in end-of-life care. Age and Ageing, 50(2), 366-369. https://doi.org/10.1093/ageing/afaa266

Healthcare aims to help older people to live well, but ultimately must also support them to die well. Most people die in old age, but predicting death in both short- and long-term is impossible for many, although not all, older people. Frail older pe... Read More about The geriatrician’s role in end-of-life care.

Measuring physical activity levels in people with mild cognitive impairment or mild dementia (2020)
Journal Article
Van Der Wardt, V., Hancox, J. E., Burgon, C., Bajwa, R., Goldberg, S., & Harwood, R. H. (2021). Measuring physical activity levels in people with mild cognitive impairment or mild dementia. Journal of Aging and Physical Activity, 29(1), 10-16. https://doi.org/10.1123/japa.2019-0234

Measuring physical activity (PA) in people with mild cognitive impairment (MCI) or dementia can be difficult. The aim was to investigate the validity and acceptability of three different PA measurement methods. The mixed-method analysis included 49... Read More about Measuring physical activity levels in people with mild cognitive impairment or mild dementia.

Protocol for the process evaluation of the Promoting Activity, Independence and stability in early Dementia (PrAISED), following changes required by the COVID-19 pandemic (2020)
Journal Article
Di Lorito, C., Bosco, A., Goldberg, S., das Nair, R., O'Brien, R., Howe, L., …Harwood, R. (2020). Protocol for the process evaluation of the Promoting Activity, Independence and stability in early Dementia (PrAISED), following changes required by the COVID-19 pandemic. BMJ Open, 10(8), https://doi.org/10.1136/bmjopen-2020-039305

Introduction. The PrAISED Randomised Controlled Trial (RCT) is evaluating a home-based, face-to-face, individually tailored, activity and exercise programme for people living with dementia. Social distancing requirements following the COVID-19 pandem... Read More about Protocol for the process evaluation of the Promoting Activity, Independence and stability in early Dementia (PrAISED), following changes required by the COVID-19 pandemic.

Association of frailty with mortality in older inpatients with Covid-19: a cohort study (2020)
Journal Article
Aw, D., Woodrow, L., Ogliari, G., & Harwood, R. (2020). Association of frailty with mortality in older inpatients with Covid-19: a cohort study. Age and Ageing, 49(6), 915-922. https://doi.org/10.1093/ageing/afaa184

Background: COVID-19 has disproportionately affected older people. Objective: to investigate whether frailty is associated with all-cause mortality in older hospital inpatients, with COVID-19. Design: cohort study Setting: secondary care acute hos... Read More about Association of frailty with mortality in older inpatients with Covid-19: a cohort study.