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Immediate breast reconstruction uptake in older women with primary breast cancer: systematic review

Lee, Rachel Xue Ning; Cardoso, Maria Joao; Cheung, Kwok Leung; Parks, Ruth M.


Rachel Xue Ning Lee

Maria Joao Cardoso

Ruth M. Parks


BACKGROUND: Postmastectomy immediate breast reconstruction (PMIBR) may improve the quality of life of patients with breast cancer, of whom older women (aged 65 years or more) are a growing proportion. This study aimed to assess PMIBR in older women with regard to underlying impediments (if any). METHODS: MEDLINE, Embase, and PubMed were searched by two independent researchers up to June 2022. Eligible studies compared PMIBR rates between younger and older women with invasive primary breast cancer. RESULTS: A total of 10 studies (2012-2020) including 466 134 women were appraised, of whom two-thirds (313 298) were younger and one-third (152 836) older. Only 10.0 per cent of older women underwent PMIBR in contrast to 45.0 per cent of younger women. Two studies explored factors affecting uptake of PMIBR in older women; surgeon-associated (usual practice), patient-associated (socioeconomic status, ethnicity, and co-morbidities), and system-associated (insurance status and hospital location) factors were identified. CONCLUSION: Uptake of PMIBR in older women is low with definable (and some correctable) barriers.


Lee, R. X. N., Cardoso, M. J., Cheung, K. L., & Parks, R. M. (2022). Immediate breast reconstruction uptake in older women with primary breast cancer: systematic review. British Journal of Surgery, 109(11), 1063-1072.

Journal Article Type Article
Acceptance Date Jul 4, 2022
Online Publication Date Aug 1, 2022
Publication Date Oct 14, 2022
Deposit Date Aug 8, 2022
Publicly Available Date Aug 8, 2022
Journal The British journal of surgery
Print ISSN 0007-1323
Electronic ISSN 1365-2168
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 109
Issue 11
Article Number znac251
Pages 1063-1072
Keywords Surgery
Public URL
Publisher URL


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