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Materiomics: a toolkit for developing new biomaterials

Hook, Andrew; Morgan, Alexander; Winkler, David A.

Authors

ANDREW HOOK ANDREW.HOOK@NOTTINGHAM.AC.UK
Nottingham Research Fellow

Alexander Morgan

David A. Winkler



Abstract

Learning Objectives
• To understand the what materiomics is and why it is required
• To become familiar with the various approaches used to design materiomic experiments
• To learn what a polymer microarray is, what it is used for and how it is produced
• To appreciate the complexity of material-biological interactions
• To become familiar with computational modelling methods as applied to biomaterials
• To gain an insight into how materiomics has and will continue to benefit tissue engineering


Scope of the chapter
The materials that are employed in regenerative medicine often react unfavourably with in vivo (induce clotting, promote bacterial infection). There is a need to develop new materials that provide the required cell response, but how is this best achieved considering the huge number of polymeric materials that could be synthesised? This chapter is a description of how materials discovery should most effectively be carried out in the developing paradigm of materiomics. We define and describe the components of this approach and methodology with the aim of providing a starting point for new users to effectively ‘dock’ into the existing research.

Publication Date Jan 1, 2015
Publisher Elsevier
Peer Reviewed Peer Reviewed
Book Title Tissue engineering. Second edition
ISBN 9780124201453
APA6 Citation Hook, A., Morgan, A., & Winkler, D. A. (2015). Materiomics: a toolkit for developing new biomaterials. In Tissue engineering. Second editionElsevier
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf
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