Troubleshooting methods for the generation of novel pseudotyped viruses
King, Barnabas; Temperton, Nigel; Grehan, Keith; Scott, Simon; Wright, Edward; Tarr, Alexander W.; Daly, Janet M.
Alexander W. Tarr
JANET DALY firstname.lastname@example.org
Professor of Viral Zoonoses
A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studies such as determining the cellular targets of the envelope protein of the virus as well as identification of potential antiviral compounds and measuring specific antibody responses. In this review, we describe the common methodologies employed to generate PVs, with a focus on approaches to improve the efficacy of PV generation.
|Journal Article Type||Article|
|Peer Reviewed||Not Peer Reviewed|
|APA6 Citation||King, B., Temperton, N., Grehan, K., Scott, S., Wright, E., Tarr, A. W., & Daly, J. M. Troubleshooting methods for the generation of novel pseudotyped viruses. Future Virology,|
|Keywords||Pseudotyped virus, pseudotypes, pseudoparticles, envelope glycoproteins|
|Related Public URLs||http://www.futuremedicine.com/loi/fvl|
|Copyright Statement||Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf|
|Additional Information||Article has been submitted for publication to Future Virology.|
Troubleshooting methods for the generation of novel pseudotyped viruses_FINAL.pdf
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf
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