Psychological interventions for adults with bipolar disorder: a systematic review and meta-analysis

Oud, Matthijs; Mayo-Wilson, Evan; Braidwood, Ruth; Schulte, Peter; Jones, Steven H.; Morriss, Richard K.; Kupka, Ralph; Cuijpers, Pim; Kendall, Tim

Abstract

Background Psychological interventions may be beneficial for bipolar disorder.
Aims Efficacy evaluation of psychological interventions for adults with bipolar disorder.
Methods A systematic review of randomised controlled trials.. Outcomes were meta-analysed using RevMan and confidence assessed using the GRADE-method.
Results We included 55 trials with 6010 participants. Moderate quality evidence associated individual psychological interventions with reduced relapses at post-treatment and follow-up, and collaborative care with a reduction in hospitalisations. . Low quality evidence associated group interventions with fewer depression relapses at post-treatment and follow-up, and family psycho-education with reduced symptoms of depression and mania at post-treatment.
Conclusions There is evidence that psychological interventions are effective for people with bipolar disorder. Limits were the very low quality of much of the evidence and therefore inconclusive. Further research should identify the most (cost)-effective interventions for each phase of this disorder.

Citation

Oud, M., Mayo-Wilson, E., Braidwood, R., Schulte, P., Jones, S. H., Morriss, R. K., …Kendall, T. (2016). Psychological interventions for adults with bipolar disorder: a systematic review and meta-analysis. British Journal of Psychiatry, 208(3), 213-222. https://doi.org/10.1192/bjp.bp.114.157123

• Journal Article Type: Article
• Online Publication Date: Jan 2, 2018
• Publication Date: Mar 1, 2016
• Deposit Date: Mar 24, 2016
• Publicly Available Date: Mar 24, 2016
• Journal: British Journal of Psychiatry
• Print ISSN: 0007-1250
• Electronic ISSN: 1472-1465
• Publisher: Cambridge University Press
• Peer Reviewed: Peer Reviewed
• Volume: 208
• Issue: 3
• Pages: 213-222
• DOI: https://doi.org/10.1192/bjp.bp.114.157123
• Public URL: https://nottingham-repository.worktribe.com/output/977949
• Publisher URL: http://dx.doi.org/10.1192/bjp.bp.114.157123
• Additional Information: This is an author-produced electronic version of an article accepted for publication in the British Journal of Psychiatry. The definitive publisher-authenticated version is available online at http://bjp.rcpsych.org)