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Hearing instruments for unilateral severe-to-profound sensorineural hearing loss in adults

Kitterick, Pádraig T.; Smith, Sandra Nelson; Lucas, Laura


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Associate Professor in Hearing Sciences Translational Hearing Research

Sandra Nelson Smith

Laura Lucas


Objectives: A systematic review of the literature and meta-analysis was conducted to assess the nature and quality of the evidence for the use of hearing instruments in adults with a unilateral severe-to-profound sensorineural hearing loss.
Design: The PubMed, EMBASE, MEDLINE, Cochrane, CINAHL and DARE databases were searched with no restrictions on language. The search included articles from the start of each database until 11th February 2015. Studies were included that: (a) assessed the impact of any form of hearing instrument, including devices that re-route signals between the ears or restore aspects of hearing to a deaf ear, in adults with a sensorineural severe-to-profound loss in one ear and normal or near-normal hearing in the other ear; (b) compared different devices or compared a device to placebo or the unaided condition; (c) measured outcomes in terms of speech perception, spatial listening, or quality of life; (d) were prospective controlled or observational studies. Studies that met prospectively-defined criteria were subjected to random-effects meta-analyses.
Results: Twenty-seven studies reported in thirty articles were included. The evidence was graded as low-to-moderate quality having been obtained primarily from observational before-after comparisons. The meta-analysis identified statistically-significant benefits to speech perception in noise for devices that re-routed the speech signals of interest from the worse ear to the better ear using either air or bone conduction (mean benefit 2.5 dB). However, these devices also degraded speech understanding significantly and to a similar extent (mean deficit 3.1 dB) when noise was re-routed to the better ear. Data on the effects of cochlear implantation on speech perception could not be pooled as the prospectively-defined criteria for meta-analysis were not met. Inconsistency in the assessment of outcomes relating to sound localisation also precluded the synthesis of evidence across studies. Evidence for the relative efficacy of different devices was sparse but a statistically significant advantage was observed for re-routing speech signals using abutment-mounted bone conduction devices when compared to outcomes after pre-operative trials of air-conduction devices when speech and noise were co-located (mean benefit 1.5 dB). Patients reported significant improvements in hearing-related quality of life with both re-routing devices and following cochlear implantation. Only two studies measured health-related quality of life and findings were inconclusive.
Conclusions: Devices that re-route sounds from an ear with a severe-to-profound hearing loss to an ear with minimal hearing loss may improve speech perception in noise when signals of interest are located towards the impaired ear. However, the same device may also degrade speech perception as all signals are re-routed indiscriminately, including noise. While the restoration of functional hearing in both ears through cochlear implantation could be expected to provide benefits to speech perception, the inability to synthesise evidence across existing studies means that such a conclusion cannot yet be made. For the same reason, it remains unclear whether cochlear implantation can improve the ability to localise sounds despite restoring bilateral input. Prospective controlled studies that measure outcomes consistently and control for selection and observation biases are required to improve the quality of the evidence for the provision of hearing instruments to patients with unilateral deafness and to support any future recommendations for the clinical management of these patients.


Kitterick, P. T., Smith, S. N., & Lucas, L. (2016). Hearing instruments for unilateral severe-to-profound sensorineural hearing loss in adults. Ear and Hearing, 37(5),

Journal Article Type Article
Acceptance Date Feb 28, 2016
Online Publication Date Aug 26, 2016
Publication Date Sep 1, 2016
Deposit Date Jan 24, 2017
Publicly Available Date Jan 24, 2017
Journal Ear and Hearing
Print ISSN 0196-0202
Electronic ISSN 1538-4667
Publisher Lippincott, Williams & Wilkins
Peer Reviewed Peer Reviewed
Volume 37
Issue 5
Keywords Air conduction; Bone conduction; Cochlear implantation; Contralateral routing of signals; Localization; Meta-analysis; Quality of life; Re-routing devices; Restorative devices; Single-sided deafness; Speech perception; Systematic review; Unilateral deafne
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Copyright Statement Copyright information regarding this work can be found at the following address:


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Copyright Statement
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