Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study

Nakafero, Georgina; Grainge, Matthew J.; Myles, Puja R.; Mallen, Christian; Zhang, Weiya; Doherty, Michael; Nguyen-Van-Tam, Jonathan S.; Abhishek, Abhishek

Abstract

Objectives: To [1] examine temporal trend in uptake of seasonal influenza vaccine (SIV) in the UK, [2] explore disease and demographic factors associated with vaccination.
Methods: 32,751 people with auto-immune rheumatic diseases (AIRDs) prescribed disease modifying anti-rheumatic drugs (DMARDs) between 2006 and 2016 were identified from the Clinical Practice Research Datalink. The proportion vaccinated between 01/September of one year and 31/March of next year was calculated and stratified by age, other indications for vaccination, AIRD type, and number of DMARDs prescribed. Stata and Joinpoint regression programs were used.
Results: SIV uptake was high in those aged ≥65 years (82.3% and 80.7% in 2006-07 and 2015-16 respectively). It was significantly lower in other age groups, but improved over time with 51.9% and 61.9% in the 45-64 year age group, and 32.3% and 50.1% in the

Citation

Nakafero, G., Grainge, M. J., Myles, P. R., Mallen, C., Zhang, W., Doherty, M., …Abhishek, A. (2018). Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study. Rheumatology, 57(10), 1726-1734. https://doi.org/10.1093/rheumatology/key156

• Journal Article Type: Article
• Acceptance Date: Apr 18, 2018
• Online Publication Date: Jun 12, 2018
• Publication Date: Oct 1, 2018
• Deposit Date: Apr 23, 2018
• Publicly Available Date: Jun 12, 2018
• Journal: Rheumatology
• Electronic ISSN: 1462-0332
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 57
• Issue: 10
• Pages: 1726-1734
• DOI: https://doi.org/10.1093/rheumatology/key156
• Keywords: rheumatoid arthritis, influenza, vaccination, disease modifying anti-rheumatic drugs
• Public URL: https://nottingham-repository.worktribe.com/output/938143
• Publisher URL: https://academic.oup.com/rheumatology/article/57/10/1726/5036781