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Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis

Shokraneh, Farhad; Adams, Clive Elliott

Authors

Farhad Shokraneh

Clive Elliott Adams



Abstract

Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented. Such registers are integral to the process of scientific reviewing. We document and discuss methodological aspects of the development and use of study-based registers. Although the content is focused on the study-based register of randomized/controlled clinical trials, this work applies to developers of databases of all sorts of studies related to the human, animals, cells, genes, and molecules.
Methods: We describe necessity, rationale, and steps for the development, utilization and maintenance of study-based registers as well as the challenges and gains for the organizations supporting systematic reviews of the published and unpublished literature.
Conclusion: The ultimate goal of having a study-based register is to facilitate efficient production of systematic reviews providing rapid, yet accurate, evidence for the decision-makers. We argue that moving towards study-based registers is an inevitable welcome direction and that infrastructures are ready for such movement.

Citation

Shokraneh, F., & Adams, C. E. (2017). Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis. Bioimpacts, 7(4), https://doi.org/10.15171/bi.2017.25

Journal Article Type Article
Acceptance Date Sep 16, 2017
Online Publication Date Sep 17, 2017
Publication Date Oct 15, 2017
Deposit Date Jan 8, 2018
Publicly Available Date Mar 29, 2024
Journal Bioimpacts
Electronic ISSN 2228-5652
Publisher Tabriz University of Medical Sciences
Peer Reviewed Peer Reviewed
Volume 7
Issue 4
DOI https://doi.org/10.15171/bi.2017.25
Public URL https://nottingham-repository.worktribe.com/output/887815
Publisher URL http://bi.tbzmed.ac.ir/Abstract/bi-17429

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