Tailored Additives for Incorporation of Antibacterial Functionality Into Laser Sintered Parts

Wingham, James R.; Ahmed, Ifty; Islam, Md Towhidul; Shepherd, Joanna; Majewski, Candice

doi:10.3389/fbiom.2022.929006

Authors

James R. Wingham

Associate Professor IFTY AHMED ifty.ahmed@nottingham.ac.uk
Associate Professor

Md Towhidul Islam

Joanna Shepherd

Candice Majewski

Abstract

Infectious disease is a major cause of death worldwide, and novel methods capable of controlling the spread of disease are in high demand. This research presents a method of producing antimicrobial microcomposites by exploiting the powder-based nature of the Laser Sintering Additive Manufacturing process, via the incorporation of silver-containing additives. Silver phosphate glass additives in different formulations were designed to determine the effect of dissolution rate on the antimicrobial efficacy. These were characterised and successfully incorporated into polyamide 12 parts, without affecting the mechanical properties. The printed microcomposite parts displayed both bactericidal and antibiofouling effects against Gram-positive and Gram-negative bacteria in nutrient-poor conditions, with the efficacy found to be more sensitive to silver content than degradation rate.

Citation

Wingham, J. R., Ahmed, I., Islam, M. T., Shepherd, J., & Majewski, C. (2022). Tailored Additives for Incorporation of Antibacterial Functionality Into Laser Sintered Parts. Frontiers in Biomaterials Science, 1, Article 929006. https://doi.org/10.3389/fbiom.2022.929006

Journal Article Type	Article
Acceptance Date	Jun 9, 2022
Online Publication Date	Jul 8, 2022
Publication Date	Jul 8, 2022
Deposit Date	Jul 8, 2022
Publicly Available Date	Jul 8, 2022
Journal	Frontiers in Biomaterials Science
Publisher	Frontiers Media
Peer Reviewed	Peer Reviewed
Volume	1
Article Number	929006
DOI	https://doi.org/10.3389/fbiom.2022.929006
Keywords	polymer laser sintering; antibacterial material; phosphate glass; microcomposite; additive manufacturing
Public URL	https://nottingham-repository.worktribe.com/output/8855376
Publisher URL	https://www.frontiersin.org/articles/10.3389/fbiom.2022.929006/full?