Skip to main content

Research Repository

Advanced Search

How to choose between measures of tinnitus loudness for clinical research?: a report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase IIa drug trial

Hall, Deborah A.; Mehta, Rajnikant; Fackrell, Kathryn L.

Authors

Profile Image

DEBORAH HALL Deborah.Hall@nottingham.ac.uk
Professor of Hearing Sciences

Rajnikant Mehta



Abstract

Purpose: Loudness is a major auditory dimension of tinnitus, and is used to diagnose severity, counsel patients or as a measure of clinical efficacy in audiological research. There is no standard test for tinnitus loudness, but matching and rating methods are popular. This article provides important new knowledge about the reliability and validity of an audiologist-administered tinnitus loudness matching test and a patient-reported tinnitus loudness rating.
Method: Retrospective analysis of loudness data for 91 participants with stable subjective tinnitus enrolled in a randomised controlled trial of a novel drug for tinnitus. There were two baseline assessments (Screening, Day1) and a post-treatment assessment (Day28).
Results: About 66-70% of the variability from Screening to Day1 was attributable to the true score. But measurement error, indicated by the Smallest Detectable Change, was high for both tinnitus loudness matching (20 dB) and tinnitus loudness rating (3.5 units). Only loudness rating captured a sensation that was meaningful to people with the lived experience of tinnitus.
Conclusions: The tinnitus loudness rating performed better against acceptability criteria for reliability and validity than did the tinnitus loudness matching test administered by an audiologist. But the rating question is still limited because it is a single-item instrument and is probably able to detect only large changes (at least 3.5 points).

Journal Article Type Article
Publication Date Sep 18, 2017
Journal American Journal of Audiology
Print ISSN 1059-0889
Electronic ISSN 1558-9137
Publisher American Speech-Language-Hearing Association
Peer Reviewed Peer Reviewed
Volume 26
APA6 Citation Hall, D. A., Mehta, R., & Fackrell, K. L. (2017). How to choose between measures of tinnitus loudness for clinical research?: a report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase IIa drug trial. American Journal of Audiology, 26, https://doi.org/10.1044/2017_AJA-16-0129
DOI https://doi.org/10.1044/2017_AJA-16-0129
Keywords Tinnitus, Adults, Outcomes
Publisher URL http://aja.pubs.asha.org/article.aspx?articleid=2652714
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

Files

Manuscript AJA-16-0129.R2.pdf (713 Kb)
PDF

Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





You might also like



Downloadable Citations

;