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Optimization of fed-batch fermentation processes using the Backtracking Search Algorithm

Zain, Mohamad Zihin bin Mohd; Kanesan, Jeevan; Kendall, G.; Chuah, Joon Huang

Authors

Mohamad Zihin bin Mohd Zain

Jeevan Kanesan

G. Kendall graham.kendall@nottingham.ac.uk

Joon Huang Chuah



Abstract

Fed-batch fermentation has gained attention in recent years due to its beneficial impact in the economy and productivity of bioprocesses. However, the complexity of these processes requires an expert system that involves swarm intelligence-based metaheuristics such as Artificial Algae Algorithm (AAA), Artificial Bee Colony (ABC), Covariance Matrix Adaptation Evolution Strategy (CMAES) and Differential Evolution (DE) for simulation and optimization of the feeding trajectories. DE traditionally performs better than other evolutionary algorithms and swarm intelligence techniques in optimization of fed-batch fermentation. In this work, an improved version of DE namely Backtracking Search Algorithm (BSA) has edged DE and other recent metaheuristics to emerge as superior optimization method. This is shown by the results obtained by comparing the performance of BSA, DE, CMAES, AAA and ABC in solving six fed batch fermentation case studies. BSA gave the best overall performance by showing improved solutions and more robust convergence in comparison with various metaheuristics used in this work. Also, there is a gap in the study of fed-batch application of wastewater and sewage sludge treatment. Thus, the fed batch fermentation problems in winery wastewater treatment and biogas generation from sewage sludge are investigated and reformulated for optimization.

Journal Article Type Article
Journal Expert Systems with Applications
Print ISSN 0957-4174
Electronic ISSN 0957-4174
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 91
APA6 Citation Zain, M. Z. B. M., Kanesan, J., Kendall, G., & Chuah, J. H. (in press). Optimization of fed-batch fermentation processes using the Backtracking Search Algorithm. Expert Systems with Applications, 91, doi:10.1016/j.eswa.2017.07.034
DOI https://doi.org/10.1016/j.eswa.2017.07.034
Keywords Fed-batch fermentation; Backtracking Search Algorithm; Evolutionary algorithms; Wastewater treatment; Feeding trajectory optimization; Sewage sludge
Publisher URL https://www.sciencedirect.com/science/article/pii/S0957417417305110?via%3Dihub
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0





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