Louise Fleming
The burden of severe asthma in childhood and adolescence: Results from the paediatric U-BIOPRED cohorts
Fleming, Louise; Murray, Clare; Bansal, Aruna T.; Hashimoto, Simone; Bisgaard, Hans; Bush, Andrew; Frey, Urs; Hedlin, Gunilla; Singer, Florian; Aalderen, Wim M. van; Vissing, Nadja H.; Zolkipli, Zaraquiza; Selby, Anna; Fowler, Stephen; Shaw, Dominick E.; Chung, Kian Fan; Sousa, Ana R.; Wagers, Scott; Corfield, Julie; Pandis, Ioannis; Rowe, Anthony; Formaggio, Elena; Sterk, Peter J.; Roberts, Graham
Authors
Clare Murray
Aruna T. Bansal
Simone Hashimoto
Hans Bisgaard
Andrew Bush
Urs Frey
Gunilla Hedlin
Florian Singer
Wim M. van Aalderen
Nadja H. Vissing
Zaraquiza Zolkipli
Anna Selby
Stephen Fowler
Dominick E. Shaw
Kian Fan Chung
Ana R. Sousa
Scott Wagers
Julie Corfield
Ioannis Pandis
Anthony Rowe
Elena Formaggio
Peter J. Sterk
Graham Roberts
Abstract
U-BIOPRED aims to characterise paediatric and adult severe asthma using conventional and innovative systems biology approaches.
A total of 99 school-age children with severe asthma and 81 preschoolers with severe wheeze were compared with 49 school-age children with mild/moderate asthma and 53 preschoolers with mild/moderate wheeze in a cross-sectional study.
Despite high-dose treatment, the severe cohorts had more severe exacerbations compared with the mild/moderate ones (annual medians: school-aged 3.0 versus 1.1, preschool 3.9 versus 1.8; p
Citation
Fleming, L., Murray, C., Bansal, A. T., Hashimoto, S., Bisgaard, H., Bush, A., …Roberts, G. (2015). The burden of severe asthma in childhood and adolescence: Results from the paediatric U-BIOPRED cohorts. European Respiratory Journal, 46(5), https://doi.org/10.1183/13993003.00780-2015
Journal Article Type | Article |
---|---|
Acceptance Date | Aug 23, 2015 |
Online Publication Date | Sep 24, 2015 |
Publication Date | Nov 1, 2015 |
Deposit Date | May 9, 2017 |
Publicly Available Date | Mar 29, 2024 |
Journal | European Respiratory Journal |
Print ISSN | 0903-1936 |
Electronic ISSN | 1399-3003 |
Publisher | European Respiratory Society |
Peer Reviewed | Peer Reviewed |
Volume | 46 |
Issue | 5 |
DOI | https://doi.org/10.1183/13993003.00780-2015 |
Public URL | https://nottingham-repository.worktribe.com/output/762346 |
Publisher URL | https://doi.org/10.1183/13993003.00780-2015 |
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