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Novel gonadal characteristics in an aged bovine freemartin

Remnant, J.G.; Lea, Richard G.; Allen, Ceri E.; Huxley, J.N.; Robinson, Robert S.; Brower, A.

Authors

JOHN REMNANT John.Remnant@nottingham.ac.uk
Clinical Associate Professor

Richard G. Lea

Ceri E. Allen

J.N. Huxley jon.huxley@nottingham.ac.uk

A. Brower



Abstract

The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cells (Sertoli cells) in the context of abundant steroidogenic interstitial cells, and structures consistent with clusters of luteal cells. This novel report describes the clinical, gross and histological findings accompanying this newly described gonadal immunophenotype, and its implication in the understanding of freemartin development.

Citation

Remnant, J., Lea, R. G., Allen, C. E., Huxley, J., Robinson, R. S., & Brower, A. (2014). Novel gonadal characteristics in an aged bovine freemartin. Animal Reproduction Science, 146(1-2), https://doi.org/10.1016/j.anireprosci.2014.02.011

Journal Article Type Article
Acceptance Date Feb 15, 2014
Online Publication Date Mar 1, 2014
Publication Date Apr 1, 2014
Deposit Date Jun 30, 2016
Publicly Available Date Jun 30, 2016
Journal Animal Reproduction Science
Print ISSN 0378-4320
Electronic ISSN 1873-2232
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 146
Issue 1-2
DOI https://doi.org/10.1016/j.anireprosci.2014.02.011
Keywords Anti-Mullerian Hormone (AMH), Bovine, CYP17A1, Freemartin, Gonad
Public URL http://eprints.nottingham.ac.uk/id/eprint/34519
Publisher URL http://www.sciencedirect.com/science/article/pii/S0378432014000517
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nd-sa/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nd-sa/4.0





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