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Novel gonadal characteristics in an aged bovine freemartin

Remnant, J.G.; Lea, Richard G.; Allen, Ceri E.; Huxley, J.N.; Robinson, Robert S.; Brower, A.

Authors

J.G. Remnant john.remnant@nottingham.ac.uk

Richard G. Lea

Ceri E. Allen

J.N. Huxley jon.huxley@nottingham.ac.uk

Robert S. Robinson

A. Brower

Abstract

The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cells (Sertoli cells) in the context of abundant steroidogenic interstitial cells, and structures consistent with clusters of luteal cells. This novel report describes the clinical, gross and histological findings accompanying this newly described gonadal immunophenotype, and its implication in the understanding of freemartin development.

Journal Article Type Article
Publication Date Apr 1, 2014
Journal Animal Reproduction Science
Print ISSN 0378-4320
Electronic ISSN 1873-2232
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 146
Issue 1-2
Institution Citation Remnant, J., Lea, R. G., Allen, C. E., Huxley, J., Robinson, R. S., & Brower, A. (2014). Novel gonadal characteristics in an aged bovine freemartin. Animal Reproduction Science, 146(1-2), doi:10.1016/j.anireprosci.2014.02.011
DOI https://doi.org/10.1016/j.anireprosci.2014.02.011
Keywords Anti-Mullerian Hormone (AMH), Bovine, CYP17A1, Freemartin, Gonad
Publisher URL http://www.sciencedirect.com/science/article/pii/S0378432014000517
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nd-sa/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nd-sa/4.0




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