Mobilizing molluscan models and genomes in biology

Davison, Angus; Neiman, Maurine

Abstract

Molluscs are among the most ancient, diverse, and important of all animal taxa. Even so, no individual mollusc species has emerged as a broadly applied model system in biology. We here make the case that both perceptual and methodological barriers have played a role in the relative neglect of molluscs as research organisms. We then summarize the current application and potential of molluscs and their genomes to address important questions in animal biology, and the state of the field when it comes to the availability of resources such as genome assemblies, cell lines, and other key elements necessary to mobilising the development of molluscan model systems. We conclude by contending that a cohesive research community that works together to elevate multiple molluscan systems to 'model' status will create new opportunities in addressing basic and applied biological problems, including general features of animal evolution. This article is part of the Theo Murphy meeting issue 'Molluscan genomics: broad insights and future directions for a neglected phylum'.

Citation

Davison, A., & Neiman, M. (2021). Mobilizing molluscan models and genomes in biology. Philosophical Transactions B: Biological Sciences, 376(1825), Article 20200163. https://doi.org/10.1098/rstb.2020.0163

• Journal Article Type: Article
• Acceptance Date: Nov 23, 2020
• Online Publication Date: Apr 5, 2021
• Publication Date: May 24, 2021
• Deposit Date: Oct 2, 2023
• Journal: Philosophical Transactions of the Royal Society B: Biological Sciences
• Print ISSN: 0962-8436
• Electronic ISSN: 1471-2970
• Publisher: The Royal Society
• Peer Reviewed: Peer Reviewed
• Volume: 376
• Issue: 1825
• Article Number: 20200163
• DOI: https://doi.org/10.1098/rstb.2020.0163
• Keywords: General Agricultural and Biological Sciences; General Biochemistry, Genetics and Molecular Biology
• Public URL: https://nottingham-repository.worktribe.com/output/5481178
• Publisher URL: https://royalsocietypublishing.org/doi/10.1098/rstb.2020.0163
• Additional Information: Accepted: 2020-11-23; Published: 2021-04-05