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Fluorescent Nanosensors: Real-Time Biochemical Measurement for Cell and Gene Therapies

CHAUHAN, VEEREN

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Abstract

Biochemical changes essential for cell growth occur within sub-cellular spaces, for which there are no readily available technologies to map their important ephemeral fluctuations. Fluorescent nanosensors, have the potential to address this challenge, due to their biocompatibility, ratiometric accuracy and real-time measurement capabilities. They have already demonstrated their potential to quantify pH, molecular oxygen and temperature in complex model systems, which include nematodes, fungi, stem cells and electronic devices. Therefore, these exciting findings could be readily translated to augment biomanufacturing for cell and gene therapy future pharmaceuticals.

Citation

CHAUHAN, V. (2020). Fluorescent Nanosensors: Real-Time Biochemical Measurement for Cell and Gene Therapies. BioProcess International, 18(3), 4-8

Journal Article Type Article
Acceptance Date May 28, 2020
Online Publication Date May 28, 2020
Publication Date May 28, 2020
Deposit Date Aug 14, 2020
Publicly Available Date Aug 21, 2020
Journal BioProcess International
Publisher Informa Connect
Peer Reviewed Not Peer Reviewed
Volume 18
Issue 3
Pages 4-8
Public URL https://nottingham-repository.worktribe.com/output/4569310
Publisher URL https://bioprocessintl.com/analytical/pat/fluorescent-nanosensors-real-time-biochemical-measurement-for-cell-and-gene-therapies/?hsCtaTracking=040bc98e-d6a1-4b56-9eee-2504a741c895%7Cd2ee4946-c873-4499-b7ec-ad2b1472c36e

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