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Future of evidence ecosystem series: 1. Introduction — Evidence synthesis ecosystem needs dramatic change

Craig, Jonathan C.; Boutron, Isabelle; Cr�quit, Perrine; Williams, Hywel; Meerpohl, Joerg; Craig, Jonathan C; Ravaud, Philippe

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Authors

Jonathan C. Craig

Isabelle Boutron

Perrine Cr�quit

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HYWEL WILLIAMS HYWEL.WILLIAMS@NOTTINGHAM.AC.UK
Professor of Dermato-Epidemiology

Joerg Meerpohl

Jonathan C Craig

Philippe Ravaud



Abstract

To make healthcare decisions, patients, clinicians, clinical practice guideline developers, researchers, policy-makers and health system managers need a comprehensive, critical, accessible, actionable and up-to-date synthesis of all available evidence in a given condition. Systematic reviews and meta-analyses are a cornerstone of healthcare decisions. However, despite the increasing number of published systematic reviews of therapeutic interventions, the current evidence synthesis ecosystem is not properly addressing stakeholders’ needs.

The current production process leads to a series of disparate systematic reviews due to erratic and inefficient planning with a process that is not always comprehensive, and is prone to bias.
Evidence synthesis depends on the quality of primary research, so primary research that is not available, is biased or selectively reported raises important concerns. Moreover, the lack of interactions between the community of primary research producers and systematic reviewers impedes the optimal use of data.

The context has considerably evolved, with ongoing research innovations, a new medical approach with the end of the one-size-fits-all approach, more available data, and new patient expectations. All these changes must be introduced into the future evidence ecosystem.

Dramatic changes are needed to enable this future ecosystem to become user-driven and user-oriented and more useful for decision-making. _

Citation

Craig, J. C., Boutron, I., Créquit, P., Williams, H., Meerpohl, J., Craig, J. C., & Ravaud, P. (2020). Future of evidence ecosystem series: 1. Introduction — Evidence synthesis ecosystem needs dramatic change. Journal of Clinical Epidemiology, 123, 135-142. https://doi.org/10.1016/j.jclinepi.2020.01.024

Journal Article Type Article
Acceptance Date Jan 7, 2020
Online Publication Date Mar 4, 2020
Publication Date 2020-07
Deposit Date Jan 14, 2020
Publicly Available Date Mar 28, 2024
Journal Journal of Clinical Epidemiology
Print ISSN 0895-4356
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 123
Pages 135-142
DOI https://doi.org/10.1016/j.jclinepi.2020.01.024
Keywords Epidemiology
Public URL https://nottingham-repository.worktribe.com/output/3722730
Publisher URL https://www.sciencedirect.com/science/article/pii/S089543561930592X?dgcid=raven_sd_aip_email