Helen C. O'Neill
Bio-electrosprayed human sperm remain viable
O'Neill, Helen C.; Maalouf, Walid E.; Harper, Joyce C.; Jayasinghe, Suwan N.
Authors
Walid E. Maalouf
Joyce C. Harper
Suwan N. Jayasinghe
Contributors
Walid Maalouf
Contact Person
Abstract
© 2019 Elsevier Ltd In our previous investigations, we demonstrated that certain living cells exposed to bio-electrosprays remained viable, and behaved as expected in comparison to control cells. These studies also extended to post-bio-electrosprayed cells being transplanted into mice, which demonstrated no rejection, and in fact they were seen to integrate with the surrounding host tissues. Therefore, highlighting bio-electrosprays as a front running bioplatform for engineering functional tissues for repair, replacement and rejuvenation of damaged and/ageing tissues. In the present studies, we take bio-electrosprays further into human health, investigating the possibility of this platform biotechnology to directly handle the smallest and most highly specialized cell in the human body, the spermatozoon. These studies demonstrated the ability for bio-electrosprays to directly handle human sperm without compromising their viability, while also demonstrating the technology's capacity to encapsulate human sperm. These investigations reported herein present interesting implications to human reproductive science and medicine, while also having promising applicability to areas such as the agriculture and aquaculture industries.
Citation
O'Neill, H. C., Maalouf, W. E., Harper, J. C., & Jayasinghe, S. N. (2019). Bio-electrosprayed human sperm remain viable. Materials Today, 31, 21-30. https://doi.org/10.1016/j.mattod.2019.10.004
Journal Article Type | Article |
---|---|
Acceptance Date | Oct 12, 2019 |
Online Publication Date | Nov 5, 2019 |
Publication Date | Dec 1, 2019 |
Deposit Date | Nov 26, 2019 |
Publicly Available Date | Nov 6, 2020 |
Journal | Materials Today |
Print ISSN | 1369-7021 |
Electronic ISSN | 1873-4103 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 31 |
Pages | 21-30 |
DOI | https://doi.org/10.1016/j.mattod.2019.10.004 |
Keywords | Mechanical Engineering; General Materials Science; Mechanics of Materials; Condensed Matter Physics |
Public URL | https://nottingham-repository.worktribe.com/output/3417423 |
Publisher URL | https://www.sciencedirect.com/science/article/pii/S1369702119308065 |
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