Rheological techniques for determining degradation of polylactic acid in bioresorbable medical polymer systems

Choong, Gabriel Y.H.; Parsons, Andrew J.; Grant, David M.; De Focatiis, Davide S.A.

Abstract

© 2015 AIP Publishing LLC. A method developed in the 1980s for the conversion of linear rheological data to molar mab distribution is revisited in the context of degradable polymers. The method is first applied using linear rheology for a linear polystyrene, for which all conversion parameters are known. A proof of principle is then carried out on four polycarbonate grades. Finally, preliminary results are shown on degradable polylactides. The application of this method to degrading polymer systems, and to systems containing nanofillers, is also discubed. This work forms part of a wider study of bioresorbable nanocomposites using polylactides, novel hydroxyapatite nanoparticles and tailored dispersants for medical applications.

Citation

Choong, G. Y., Parsons, A. J., Grant, D. M., & De Focatiis, D. S. (2015). Rheological techniques for determining degradation of polylactic acid in bioresorbable medical polymer systems. AIP Conference Proceedings, 1664, Article 170005. https://doi.org/10.1063/1.4918523

• Journal Article Type: Conference Paper
• Acceptance Date: May 22, 2015
• Online Publication Date: May 22, 2015
• Publication Date: May 22, 2015
• Deposit Date: Sep 2, 2020
• Publicly Available Date: Sep 18, 2020
• Journal: AIP Conference Proceedings
• Print ISSN: 0094-243X
• Electronic ISSN: 1551-7616
• Publisher: American Institute of Physics
• Peer Reviewed: Peer Reviewed
• Volume: 1664
• Article Number: 170005
• DOI: https://doi.org/10.1063/1.4918523
• Public URL: https://nottingham-repository.worktribe.com/output/3187901
• Publisher URL: https://aip.scitation.org/doi/abs/10.1063/1.4918523