Einar Vargas-Bello-P�rez
Long-Term Effects of Dietary Olive Oil and Hydrogenated Vegetable Oil on Expression of Lipogenic Genes in Subcutaneous Adipose Tissue of Dairy Cows
Vargas-Bello-P�rez, Einar; Bionaz, Massimo; Sciarresi-Arechabala, Pietro; Cancino-Padilla, Nathaly; Sol Morales, Mar�a; Romero, Jaime; Leskinen, Heidi; Garnsworthy, Philip C.; Loor, Juan J.
Authors
Massimo Bionaz
Pietro Sciarresi-Arechabala
Nathaly Cancino-Padilla
Mar�a Sol Morales
Jaime Romero
Heidi Leskinen
Philip C. Garnsworthy
Juan J. Loor
Abstract
The objective of this study was to characterize the long-term transcriptomic effects of lipogenic genes in subcutaneous adipose tissue (SAT) of dairy cows supplemented with unsaturated (olive oil; OO) and saturated (hydrogenated vegetable oil; HVO) lipids. Cows were fed a control diet with no added lipid, or diets containing OO or HVO (n = 5 cows/group) for 63 days. SAT was obtained from the tail-head area at the onset of the study and after 21, 42, and 63 days of supplementation. Treatments had minor effects on expression of measured genes. Both fat supplements reduced expression of PPARG, HVO decreased transcription of the desaturase FADS2 and lipid droplet formation PLIN2, and OO increased transcription of FABP3. Both lipid treatments decreased expression of the transcription regulator SREBF1 and its chaperone (SCAP) during the first 21 days of treatment. Our data indicated that long-term feeding of OO and HVO have a relatively mild effect on expression of lipogenic genes in SAT of mid-lactating cows.
Citation
Vargas-Bello-Pérez, E., Bionaz, M., Sciarresi-Arechabala, P., Cancino-Padilla, N., Sol Morales, M., Romero, J., …Loor, J. J. (2019). Long-Term Effects of Dietary Olive Oil and Hydrogenated Vegetable Oil on Expression of Lipogenic Genes in Subcutaneous Adipose Tissue of Dairy Cows. Veterinary Sciences, 6(3), https://doi.org/10.3390/vetsci6030074
Journal Article Type | Article |
---|---|
Acceptance Date | Sep 12, 2019 |
Online Publication Date | Sep 15, 2019 |
Publication Date | Sep 15, 2019 |
Deposit Date | Sep 26, 2019 |
Publicly Available Date | Mar 28, 2024 |
Journal | Veterinary Sciences |
Electronic ISSN | 2306-7381 |
Publisher | MDPI |
Peer Reviewed | Peer Reviewed |
Volume | 6 |
Issue | 3 |
Article Number | 74 |
DOI | https://doi.org/10.3390/vetsci6030074 |
Keywords | Fat supplementation; Transcriptomics; Adipose tissue; Lipid metabolism; Lipogenic gene expression; Dairy cows |
Public URL | https://nottingham-repository.worktribe.com/output/2664704 |
Publisher URL | https://www.mdpi.com/2306-7381/6/3/74 |
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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