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Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis

Grootveld, Martin; Percival, Benita; Gibson, Miles; Osman, Yasan; Edgar, Mark; Molinari, Marco; Mather, Melissa L.; Casanova, Federico; Wilson, Philippe B.


Martin Grootveld

Benita Percival

Miles Gibson

Yasan Osman

Mark Edgar

Marco Molinari

Federico Casanova

Philippe B. Wilson



© 2019 Elsevier B.V. The employment of spectroscopically-resolved NMR techniques as analytical probes have previously been both prohibitively expensive and logistically challenging in view of the large sizes of high-field facilities. However, with recent advances in the miniaturisation of magnetic resonance technology, low-field, cryogen-free “benchtop” NMR instruments are seeing wider use. Indeed, these miniaturised spectrometers are utilised in areas ranging from food and agricultural analyses, through to human biofluid assays and disease monitoring. Therefore, it is both intrinsically timely and important to highlight current applications of this analytical strategy, and also provide an outlook for the future, where this approach may be applied to a wider range of analytical problems, both qualitatively and quantitatively.

Journal Article Type Article
Acceptance Date Feb 19, 2019
Online Publication Date Feb 23, 2019
Publication Date Aug 27, 2019
Deposit Date May 28, 2019
Journal Analytica Chimica Acta
Print ISSN 0003-2670
Electronic ISSN 1873-4324
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 1067
Pages 11-30
Keywords Analytical Chemistry; Spectroscopy; Biochemistry; Environmental Chemistry
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