Dr MATTHEW WADGE Matthew.Wadge3@nottingham.ac.uk
Research Fellow
Developing alkaline titanate surfaces for medical applications
Wadge, Matthew D.; McGuire, Jamie; Thomas, Kathryn G.; Stuart, Bryan W.; Felfel, Reda M.; Ahmed, Ifty; Grant, David M.
Authors
Jamie McGuire
Kathryn G. Thomas
Bryan W. Stuart
Reda M. Felfel
Associate Professor IFTY AHMED ifty.ahmed@nottingham.ac.uk
Associate Professor
DAVID GRANT DAVID.GRANT@NOTTINGHAM.AC.UK
Professor of Materials Science
Abstract
Improving the surface of medical implants by plasma spraying of a hydroxyapatite coating can be of critical importance to their longevity and the patient’s convalescence. However, residual stresses, cracking, undesired crystallisation and delamination of the coating compromise the implants lifetime. A promising alternative surface application is an alkali-chemical treatment to generate bioactive surfaces, such as sodium and calcium titanate and their derivatives. Such surfaces obviate the need for high temperatures and resulting micro-crack formation and potentially improve the bioactive and bone integration properties through their nanoporous structures. Also, metallic ions such as silver, gallium and copper can be substituted into the titanate structure with the potential to reduce or eliminate the infections. This review examines the formation and mechanisms of bioactive/antibacterial alkaline titanate surfaces, their successes and limitations, and explores the future development of implant interfaces via multifunctional titanate surfaces on Ti-based alloys and on alternative substrate materials.
Citation
Wadge, M. D., McGuire, J., Thomas, K. G., Stuart, B. W., Felfel, R. M., Ahmed, I., & Grant, D. M. (in press). Developing alkaline titanate surfaces for medical applications. International Materials Reviews, Article 2153217. https://doi.org/10.1080/09506608.2022.2153217
Journal Article Type | Article |
---|---|
Acceptance Date | Nov 22, 2022 |
Online Publication Date | Jan 24, 2023 |
Deposit Date | Mar 31, 2023 |
Publicly Available Date | Mar 29, 2024 |
Journal | International Materials Reviews |
Print ISSN | 0950-6608 |
Electronic ISSN | 1743-2804 |
Publisher | Informa UK Limited |
Peer Reviewed | Peer Reviewed |
Article Number | 2153217 |
DOI | https://doi.org/10.1080/09506608.2022.2153217 |
Keywords | Titanate; biomaterial; implant; surface; modification; substitution; antibacterial; bioactive; multifunctional |
Public URL | https://nottingham-repository.worktribe.com/output/16506690 |
Publisher URL | https://www.tandfonline.com/doi/full/10.1080/09506608.2022.2153217 |
Additional Information | © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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Copyright Statement
© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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