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Evolution of treatment targets in Crohn’s disease

White, Jonathan R.; Jairath, Vipul; Moran, Gordon W.

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Authors

Jonathan R. White

Vipul Jairath

GORDON MORAN GORDON.MORAN@NOTTINGHAM.AC.UK
Professor of Gastroenterology



Abstract

Crohn’s disease is a chronic relapsing and remitting inflammatory disorder of the gastrointestinal tract, associated with significantly morbidity due to both symptoms and complications that have a considerable detrimental impact on a patient’s quality of life. An early treat to target approach with disease modifying agents has been shown to significantly improve long term outcomes, demonstrated by a number of therapeutic targets in a number of modalities. This review will outline the current treatment targets and measures of disease burden in Crohn’s disease.

Citation

White, J. R., Jairath, V., & Moran, G. W. (2019). Evolution of treatment targets in Crohn’s disease. Best Practice and Research: Clinical Gastroenterology, 38-39, 1-9. https://doi.org/10.1016/j.bpg.2019.02.001

Journal Article Type Article
Acceptance Date Feb 14, 2019
Online Publication Date Feb 16, 2019
Publication Date 2019-02
Deposit Date Feb 20, 2019
Publicly Available Date Feb 17, 2020
Journal Best Practice & Research Clinical Gastroenterology
Print ISSN 1521-6918
Electronic ISSN 1532-1916
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 38-39
Article Number 101599
Pages 1-9
DOI https://doi.org/10.1016/j.bpg.2019.02.001
Keywords Crohn’s disease; Treatment targets; Patient reported outcomes; Clinician reported activity indices; Biomarkers; Endoscopy; Imaging; Histology
Public URL https://nottingham-repository.worktribe.com/output/1572006
Publisher URL https://www.sciencedirect.com/science/article/pii/S1521691819300022?via%3Dihub
Contract Date Feb 20, 2019

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