Jonathan R. White
Evolution of treatment targets in Crohn’s disease
White, Jonathan R.; Jairath, Vipul; Moran, Gordon W.
GORDON MORAN GORDON.MORAN@NOTTINGHAM.AC.UK
Clinical Associate Professor
Crohn’s disease is a chronic relapsing and remitting inflammatory disorder of the gastrointestinal tract, associated with significantly morbidity due to both symptoms and complications that have a considerable detrimental impact on a patient’s quality of life. An early treat to target approach with disease modifying agents has been shown to significantly improve long term outcomes, demonstrated by a number of therapeutic targets in a number of modalities. This review will outline the current treatment targets and measures of disease burden in Crohn’s disease.
White, J. R., Jairath, V., & Moran, G. W. (2019). Evolution of treatment targets in Crohn’s disease. Best Practice and Research: Clinical Gastroenterology, 38-39, 1-9. https://doi.org/10.1016/j.bpg.2019.02.001
|Journal Article Type||Article|
|Acceptance Date||Feb 14, 2019|
|Online Publication Date||Feb 16, 2019|
|Deposit Date||Feb 20, 2019|
|Publicly Available Date||Feb 17, 2020|
|Journal||Best Practice & Research Clinical Gastroenterology|
|Peer Reviewed||Peer Reviewed|
|Keywords||Crohn’s disease; Treatment targets; Patient reported outcomes; Clinician reported activity indices; Biomarkers; Endoscopy; Imaging; Histology|
Final Manuscript Evolution Of Treatment Targets In Crohn 16012019 PDF