Skip to main content

Research Repository

Advanced Search

Evolution of treatment targets in Crohn’s disease

White, Jonathan R.; Jairath, Vipul; Moran, Gordon W.

Evolution of treatment targets in Crohn’s disease Thumbnail


Jonathan R. White

Vipul Jairath

Professor of Gastroenterology


Crohn’s disease is a chronic relapsing and remitting inflammatory disorder of the gastrointestinal tract, associated with significantly morbidity due to both symptoms and complications that have a considerable detrimental impact on a patient’s quality of life. An early treat to target approach with disease modifying agents has been shown to significantly improve long term outcomes, demonstrated by a number of therapeutic targets in a number of modalities. This review will outline the current treatment targets and measures of disease burden in Crohn’s disease.


White, J. R., Jairath, V., & Moran, G. W. (2019). Evolution of treatment targets in Crohn’s disease. Best Practice and Research: Clinical Gastroenterology, 38-39, 1-9.

Journal Article Type Article
Acceptance Date Feb 14, 2019
Online Publication Date Feb 16, 2019
Publication Date 2019-02
Deposit Date Feb 20, 2019
Publicly Available Date Feb 17, 2020
Journal Best Practice & Research Clinical Gastroenterology
Print ISSN 1521-6918
Electronic ISSN 1532-1916
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 38-39
Article Number 101599
Pages 1-9
Keywords Crohn’s disease; Treatment targets; Patient reported outcomes; Clinician reported activity indices; Biomarkers; Endoscopy; Imaging; Histology
Public URL
Publisher URL
Contract Date Feb 20, 2019


Downloadable Citations