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Brief report: autism spectrum disorder: a comprehensive survey of randomized controlled trials

Tromans, Samuel; Adams, Clive

Authors

Samuel Tromans

Clive Adams



Abstract

We searched the Cochrane Central Register of Controlled Trials to provide an overview of evidence from randomized con-
trolled trials (RCTs) of therapeutic interventions for autism spectrum disorders. From the final survey (529 RCTs), the mean
size was 49 participants (standard deviation 50, range 1–479, median 36, mode 40), with a sharp increase in the number of
RCTs from 2008. The most frequently evaluated intervention was antipsychotic treatment (n = 44, 3006 participants). The
journal with the most RCTs was the Journal of Autism and Developmental Disorders (N = 104). Most trials were small in
size, emphasising the need for research groups to collaborate to generate higher quality data with greater applicability to
clinical practice.

Journal Article Type Article
Publication Date Sep 28, 2018
Journal Journal of Autism and Developmental Disorders
Print ISSN 0162-3257
Electronic ISSN 1573-3432
Publisher BMC
Peer Reviewed Peer Reviewed
Volume 48
Issue 9
Pages 3228-3232
APA6 Citation Tromans, S., & Adams, C. (2018). Brief report: autism spectrum disorder: a comprehensive survey of randomized controlled trials. Journal of Autism and Developmental Disorders, 48(9), 3228-3232. doi:10.1007/s10803-018-3569-y
DOI https://doi.org/10.1007/s10803-018-3569-y
Keywords Developmental and Educational Psychology
Publisher URL https://link.springer.com/article/10.1007%2Fs10803-018-3569-y


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