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Brief Report: Autism Spectrum Disorder: A Comprehensive Survey of Randomized Controlled Trials

Tromans, Samuel; Adams, Clive

Authors

Samuel Tromans

Clive Adams



Abstract

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. We searched the Cochrane Central Register of Controlled Trials to provide an overview of evidence from randomized controlled trials (RCTs) of therapeutic interventions for autism spectrum disorders. From the final survey (529 RCTs), the mean size was 49 participants (standard deviation 50, range 1–479, median 36, mode 40), with a sharp increase in the number of RCTs from 2008. The most frequently evaluated intervention was antipsychotic treatment (n = 44, 3006 participants). The journal with the most RCTs was the Journal of Autism and Developmental Disorders (N = 104). Most trials were small in size, emphasising the need for research groups to collaborate to generate higher quality data with greater applicability to clinical practice.

Citation

Tromans, S., & Adams, C. (2018). Brief Report: Autism Spectrum Disorder: A Comprehensive Survey of Randomized Controlled Trials. Journal of Autism and Developmental Disorders, 48(9), 3228-3232. https://doi.org/10.1007/s10803-018-3569-y

Journal Article Type Article
Acceptance Date Mar 12, 2018
Online Publication Date Apr 11, 2018
Publication Date Sep 1, 2018
Deposit Date Dec 7, 2018
Publicly Available Date Mar 28, 2024
Journal Journal of Autism and Developmental Disorders
Print ISSN 0162-3257
Electronic ISSN 1573-3432
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 48
Issue 9
Pages 3228-3232
DOI https://doi.org/10.1007/s10803-018-3569-y
Keywords Developmental and Educational Psychology
Public URL https://nottingham-repository.worktribe.com/output/1385053
Publisher URL https://link.springer.com/article/10.1007%2Fs10803-018-3569-y