MERITXELL CANALS M.CANALS@NOTTINGHAM.AC.UK
Professor of Cellular Pharmacology
The complex roles of ?-opioid receptor phosphorylation: A key determinant in receptor signaling and regulation
Canals, Meritxell
Authors
Abstract
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics. This Commentary focuses on two articles in the October 2015 issue of Molecular Pharmacology that investigate the role of μ-opioid receptor phosphorylation in receptor agonist binding and desensitization. The work of Birdsong et al. and Yousuf et al. clearly highlights the complexity that researchers face when trying to assess the signaling and regulatory consequences of G protein-coupled receptor phosphorylation.
Citation
Canals, M. (2015). The complex roles of ?-opioid receptor phosphorylation: A key determinant in receptor signaling and regulation. Molecular Pharmacology, 88(4), 814-815. https://doi.org/10.1124/mol.115.100180
Journal Article Type | Review |
---|---|
Acceptance Date | Jul 7, 2015 |
Online Publication Date | Jul 7, 2015 |
Publication Date | Jul 7, 2015 |
Deposit Date | Jan 17, 2020 |
Journal | Molecular Pharmacology |
Print ISSN | 0026-895X |
Electronic ISSN | 1521-0111 |
Publisher | American Society for Pharmacology and Experimental Therapeutics |
Peer Reviewed | Peer Reviewed |
Volume | 88 |
Issue | 4 |
Pages | 814-815 |
DOI | https://doi.org/10.1124/mol.115.100180 |
Keywords | G protein coupled receptor; metenkephalin; morphine; mu opiate receptor; enkephalin[2 dextro alanine 4 methylphenylalanine 5 glycine]; mu opiate receptor; protein binding; binding affinity; carboxy terminal sequence; human; ligand binding; priority journa |
Public URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946573802&doi=10.1124%2fmol.115.100180&partnerID=40&md5=3891c7cd7d60f7558cf4b6ff140362d4 |
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