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Early Diagnosis and Lung Cancer Screening

Balata, Haval; Quaife, Samantha L.; Craig, Christopher; Ryan, Daniel J.; Bradley, Patrick; Crosbie, Philip A. J.; Murray, Rachael L.; Evison, Matthew


Haval Balata

Samantha L. Quaife

Christopher Craig

Daniel J. Ryan

Patrick Bradley

Philip A. J. Crosbie

Matthew Evison


Lung cancer remains the most significant cause of cancer death, accounting for about 20% of all cancer-related mortality. A significant reason for this is delayed diagnosis, either due to lack of symptoms in early-stage disease or presentation with non-specific symptoms common with a broad range of alternative diagnoses. More is needed in terms of increasing public awareness, providing adequate healthcare professional education and implementing clinical pathways that improve the earlier diagnosis of symptomatic lung cancer. Low-dose computed tomography screening of high-risk, asymptomatic populations has been shown to reduce lung cancer mortality, with focus now shifting towards how best to implement lung cancer screening on a wider scale in a safe, efficient and cost-effective manner. For maximum benefit, efforts must be made to optimise uptake, especially among high-risk populations with significant socioeconomic deprivation, as well as successfully incorporate tobacco-dependency treatment. Quality assured programme management will be critical to minimising screening-related harms and adequately managing incidental findings. By undertaking the above, there can be optimism that lung cancer outcomes can be improved significantly in the near future.


Balata, H., Quaife, S. L., Craig, C., Ryan, D. . J., Bradley, P., Crosbie, P. A. J., …Evison, M. (2022). Early Diagnosis and Lung Cancer Screening. Clinical Oncology, 34(11), 708-715.

Journal Article Type Article
Acceptance Date Aug 31, 2022
Online Publication Date Sep 26, 2022
Publication Date 2022-11
Deposit Date Oct 14, 2022
Publicly Available Date Sep 27, 2023
Journal Clinical Oncology
Print ISSN 0936-6555
Electronic ISSN 1433-2981
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 34
Issue 11
Pages 708-715
Keywords Radiology, Nuclear Medicine and imaging; Oncology
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