Marta Ribiero Hentchke
Negative correlation between Placental Growth Factor and Endocan-1 in women with preeclampsia
Hentchke, Marta Ribiero; da Cunha Filho, Edson Vieira; Vieira, Matias Costa; Paula, Letícia Germany; Mistry, Hiten D.; Pinheiro da Costa, Bartira Ercília; Poli-de-Figueiredo, Carlos Eduardo
Authors
Edson Vieira da Cunha Filho
Matias Costa Vieira
Letícia Germany Paula
Hiten D. Mistry
Bartira Ercília Pinheiro da Costa
Carlos Eduardo Poli-de-Figueiredo
Abstract
Objective: To analyse Endocan-1, a biomarker of vascular endothelial related pathologies, and Placental growth factor (PlGF), an angiogenic factor and a placental dysfunction marker in patients with pre-eclampsia (PE).
Methods: Case-control study conducted at São Lucas Hospital. Endocan-1 and PlGF levels were quantified in maternal plasma using MagPlexTH-C microspheres system and analysed by ANCOVA adjusted by BMI, gestational age and maternal age. To estimate the difference between groups, mean ratio (MR) and 95% confidence interval (CI) were calculated. Pearson correlation test was used to establish any association between Endocan-1 and PlGF levels. The null hypothesis was rejected when p
Citation
Hentchke, M. R., da Cunha Filho, E. V., Vieira, M. C., Paula, L. G., Mistry, H. D., Pinheiro da Costa, B. E., & Poli-de-Figueiredo, C. E. (2018). Negative correlation between Placental Growth Factor and Endocan-1 in women with preeclampsia. Revista Brasileira de Ginecologia e Obstetrícia, 40(10), 593-598. https://doi.org/10.1055/s-0038-1670713
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 2, 2018 |
Online Publication Date | Oct 23, 2018 |
Publication Date | Oct 31, 2018 |
Deposit Date | Aug 15, 2018 |
Publicly Available Date | Mar 29, 2024 |
Print ISSN | 0100-7203 |
Electronic ISSN | 1806-9339 |
Publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
Peer Reviewed | Peer Reviewed |
Volume | 40 |
Issue | 10 |
Pages | 593-598 |
DOI | https://doi.org/10.1055/s-0038-1670713 |
Keywords | Pregnancy-induced hypertension; Preeclampsia; Endothelial function; Biomarkers; Preeclampsia, cytokines |
Public URL | https://nottingham-repository.worktribe.com/output/1034352 |
Publisher URL | https://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1670713 |
Related Public URLs | http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-7203&lng=en&nrm=iso |
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Negative Correlation between Placental Growth Factor and Endocan-1 in Women with Preeclampsia
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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