Outputs (191)

Genomic and phenotypic characterisation of Pseudomonas aeruginosa isolates from canine otitis externa reveals high-risk sequence types identical to those found in human nosocomial infections (2025)
Journal Article
Secker, B., Shaw, S., Hobley, L., & Atterbury, R. J. (2025). Genomic and phenotypic characterisation of Pseudomonas aeruginosa isolates from canine otitis externa reveals high-risk sequence types identical to those found in human nosocomial infections. Frontiers in Microbiology, 16, Article 1526843. https://doi.org/10.3389/fmicb.2025.1526843

Introduction:

Canine otitis externa (OE) is a frequently-diagnosed condition in veterinary practices worldwide. Pseudomonas aeruginosa is commonly associated with chronic and recalcitrant canine OE, but studies with detailed genomic and phenotypi... Read More about Genomic and phenotypic characterisation of Pseudomonas aeruginosa isolates from canine otitis externa reveals high-risk sequence types identical to those found in human nosocomial infections.

Valorisation of hop leaves for their bioactive compounds: Identification and quantification of phenolics across different varieties, crop years and stages of development (2024)
Journal Article
Calvert, D., Dew, T., Gadon, A., Gros, J., & Cook, D. (2025). Valorisation of hop leaves for their bioactive compounds: Identification and quantification of phenolics across different varieties, crop years and stages of development. Food Chemistry, 465(Part 2), Article 142005. https://doi.org/10.1016/j.foodchem.2024.142005

Hop leaves, a by-product from hop cone harvesting, contain phenolic compounds of potential value for food or beverage applications. However, the abundant phenolics in hop leaves remain largely unquantified. This study quantified phenolics in hop leav... Read More about Valorisation of hop leaves for their bioactive compounds: Identification and quantification of phenolics across different varieties, crop years and stages of development.

Multiplexing projects: supervising undergraduate research projects with larger cohorts (2024)
Journal Article
Nisbet, R. E. R., Scott, D. J., & Campeotto, I. (2024). Multiplexing projects: supervising undergraduate research projects with larger cohorts. The Biochemist, 46(5), 18-23. https://doi.org/10.1042/BIO_2024_897

Almost all undergraduate students in the UK complete a final year research project or dissertation. In the molecular biosciences field, these projects are often based in individual research laboratory. However, with increasing student numbers, fallin... Read More about Multiplexing projects: supervising undergraduate research projects with larger cohorts.

Impacts of starch breakdown during germination and stewing on aroma formation in crystal malts (2024)
Journal Article
Foulkes, A. R., Bolat, I., Dodds, C., & Cook, D. J. (2024). Impacts of starch breakdown during germination and stewing on aroma formation in crystal malts. Journal of the Institute of Brewing, 130(4), 221-237. https://doi.org/10.58430/jib.v130i4.60

Why was the work done: Crystal malts are used in brewing to add colour, flavour and mouthfeel to beers. In their manufacture, aroma compounds are formed through thermal flavour generation during roasting of stewed green malt. As part of a wider proje... Read More about Impacts of starch breakdown during germination and stewing on aroma formation in crystal malts.

Extreme enthalpy‒entropy compensation in the dimerization of small solutes in aqueous solution (2024)
Journal Article
Scott, D. J., & Winzor, D. J. (2024). Extreme enthalpy‒entropy compensation in the dimerization of small solutes in aqueous solution. European Biophysics Journal, 53, 373-384. https://doi.org/10.1007/s00249-024-01722-y

This communication summarizes findings from the earliest encounters with extreme enthalpy‒entropy compensation, a phenomenon first detected in the 1950s by a reappraisal of isopiestic and calorimetric measurements on aqueous urea solutions in terms o... Read More about Extreme enthalpy‒entropy compensation in the dimerization of small solutes in aqueous solution.

Is there reversible dimerization of albumin in blood plasma? And does it matter? (2024)
Journal Article
Harris, G., Bradshaw, M. L., Halsall, D. J., Scott, D. J., Unwin, R. J., & Norden, A. G. W. (2024). Is there reversible dimerization of albumin in blood plasma? And does it matter?. Experimental Physiology, 109(10), 1663-1671. https://doi.org/10.1113/EP092012

Most albumin in blood plasma is thought to be monomeric with some 5% covalently dimerized. However, many reports in the recent biophysics literature find that albumin is reversibly dimerized or even oligomerized. We review data on this from X‐ray cry... Read More about Is there reversible dimerization of albumin in blood plasma? And does it matter?.

Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella (2024)
Journal Article
Richards, P. J., Almutrafy, A., Liang, L., Flaujac Lafontaine, G. M., King, E., Fish, N. M., Connerton, A. J., Connerton, P. L., & Connerton, I. F. (2024). Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella. mSystems, 9(8), Article e00754-24. https://doi.org/10.1128/msystems.00754-24

Chicken meat is contaminated with Salmonella from the gut of infected chickens during slaughter. Eradication of Salmonella from broiler chickens through hygiene measures and/or vaccination is not cost-effective; complementary approaches are required.... Read More about Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella.

Influence of ripening stage on the microwave-assisted pectin extraction from banana peels: A feasibility study targeting both the Homogalacturonan and Rhamnogalacturonan-I region. (2024)
Journal Article
Mao, Y., Dewi, S. R., Harding, S. E., & Binner, E. (2024). Influence of ripening stage on the microwave-assisted pectin extraction from banana peels: A feasibility study targeting both the Homogalacturonan and Rhamnogalacturonan-I region. Food Chemistry, 460(Pt 1), Article 140549. https://doi.org/10.1016/j.foodchem.2024.140549

This work investigated a sustainable and efficient approach of pectin extraction for banana peel waste valorisation and studied the influence of banana ripening stages (RS at 2,5 and 7). Although pectin content in banana peel raw material decreased d... Read More about Influence of ripening stage on the microwave-assisted pectin extraction from banana peels: A feasibility study targeting both the Homogalacturonan and Rhamnogalacturonan-I region..

Pilot Evaluation of S-(3-[18F]Fluoropropyl)-d-Homocysteine and O-(2-[18F]Fluoroethyl)-d-Tyrosine as Bacteria-Specific Radiotracers for PET Imaging of Infection (2024)
Journal Article
Betts, H. M., Luckett, J. C., & Hill, P. J. (2024). Pilot Evaluation of S-(3-[18F]Fluoropropyl)-d-Homocysteine and O-(2-[18F]Fluoroethyl)-d-Tyrosine as Bacteria-Specific Radiotracers for PET Imaging of Infection. Molecular Imaging and Biology, 26, 704-713. https://doi.org/10.1007/s11307-024-01929-7

Purpose There is currently no ideal radiotracer for imaging bacterial infections. Radiolabelled d-amino acids are promising candidates because they are actively incorporated into the peptidoglycan of the bacterial cell wall, a structural feature whic... Read More about Pilot Evaluation of S-(3-[18F]Fluoropropyl)-d-Homocysteine and O-(2-[18F]Fluoroethyl)-d-Tyrosine as Bacteria-Specific Radiotracers for PET Imaging of Infection.

Storability and Brewing Quality of Corn Grits: Impacts of Storage Temperature, Particle Size and Key Compositional Factors (2024)
Journal Article
Maia, C., & Cook, D. J. (2025). Storability and Brewing Quality of Corn Grits: Impacts of Storage Temperature, Particle Size and Key Compositional Factors. Journal of The American Society of Brewing Chemists, 83(1), 30-38. https://doi.org/10.1080/03610470.2024.2338609

Across international brewing operations corn grits from different suppliers vary substantially in terms of their physical properties and chemical composition. Present research aimed to highlight the key factors determining the brewing quality of stor... Read More about Storability and Brewing Quality of Corn Grits: Impacts of Storage Temperature, Particle Size and Key Compositional Factors.