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The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D., Boto, E., Holmes, N., Hill, R. M., …Brookes, M. J. (2024). The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study. eLife, Article 94561v1. https://doi.org/10.7554/eLife.94561.1

Neural oscillations mediate coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only a critical neuroscientific question but could also shed light on... Read More about The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study.

Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping (2023)
Journal Article
Hobson, P. J., Hardwicke, N. L., Davis, A., Smith, T. X., Morley, C., Packer, M., …Fromhold, M. (2023). Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping. IEEE Transactions on Instrumentation and Measurement, 72, Article 1005815. https://doi.org/10.1109/TIM.2023.3284138

Adaptable, low-cost, coils designed by carefully selecting the arrangements and geometries of simple primitive units are used to generate magnetic fields for diverse applications. These extend from magnetic resonance and fundamental physics experimen... Read More about Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping.

Test-retest reliability of the human connectome: An OPM-MEG study (2023)
Journal Article
Rier, L., Michelmann, S., Ritz, H., Shah, V., Hill, R. M., Osborne, J., …Boto, E. (2023). Test-retest reliability of the human connectome: An OPM-MEG study. Imaging Neuroscience, 1, 1-20. https://doi.org/10.1162/imag_a_00020

Magnetoencephalography with optically pumped magnetometers (OPM-MEG) offers a new way to record electrophysiological brain function, with significant advantages over conventional MEG, including adaptability to head shape/size, free movement during sc... Read More about Test-retest reliability of the human connectome: An OPM-MEG study.

Benchtop magnetic shielding for benchmarking atomic magnetometers (2023)
Journal Article
Hobson, P. J., Holmes, N., Patel, P., Styles, B., Chalmers, J., Morley, C., …Fromhold, M. (2023). Benchtop magnetic shielding for benchmarking atomic magnetometers. IEEE Transactions on Instrumentation and Measurement, 72, Article 6007309. https://doi.org/10.1109/tim.2023.3293540

Here, a benchtop hybrid magnetic shield containing four mumetal cylinders and nine internal flexible printed circuit boards is designed, constructed, tested, and operated. The shield is designed specifically as a test-bed for building and operating u... Read More about Benchtop magnetic shielding for benchmarking atomic magnetometers.

An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts (2023)
Journal Article
Holmes, N., Bowtell, R., Brookes, M. J., & Taulu, S. (2023). An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts. Sensors, 23(14), Article 6537. https://doi.org/10.3390/s23146537

The signal space separation (SSS) method is routinely employed in the analysis of multichannel magnetic field recordings (such as magnetoencephalography (MEG) data). In the SSS method, signal vectors are posed as a multipole expansion of the magnetic... Read More about An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts.

Naturalistic Hyperscanning with Wearable Magnetoencephalography (2023)
Journal Article
Holmes, N., Rea, M., Hill, R. M., Boto, E., Leggett, J., Edwards, L. J., …Bowtell, R. (2023). Naturalistic Hyperscanning with Wearable Magnetoencephalography. Sensors, 23(12), Article 5454. https://doi.org/10.3390/s23125454

The evolution of human cognitive function is reliant on complex social interactions which form the behavioural foundation of who we are. These social capacities are subject to dramatic change in disease and injury; yet their supporting neural substra... Read More about Naturalistic Hyperscanning with Wearable Magnetoencephalography.

Enabling ambulatory movement in wearable magnetoencephalography with matrix coil active magnetic shielding (2023)
Journal Article
Holmes, N., Rea, M., Hill, R. M., Leggett, J., Edwards, L. J., Hobson, P. J., …Bowtell, R. (2023). Enabling ambulatory movement in wearable magnetoencephalography with matrix coil active magnetic shielding. NeuroImage, 274, Article 120157. https://doi.org/10.1016/j.neuroimage.2023.120157

The ability to collect high-quality neuroimaging data during ambulatory participant movement would enable a wealth of neuroscientific paradigms. Wearable magnetoencephalography (MEG) based on optically pumped magnetometers (OPMs) has the potential to... Read More about Enabling ambulatory movement in wearable magnetoencephalography with matrix coil active magnetic shielding.

Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers (2023)
Journal Article
Hillebrand, A., Holmes, N., Sijsma, N., O’Neill, G. C., Tierney, T. M., Liberton, N., …Barnes, G. R. (2023). Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers. Scientific Reports, 13(1), Article 4623. https://doi.org/10.1038/s41598-023-31111-y

Magneto- and electroencephalography (MEG/EEG) are important techniques for the diagnosis and pre-surgical evaluation of epilepsy. Yet, in current cryogen-based MEG systems the sensors are offset from the scalp, which limits the signal-to-noise ratio... Read More about Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers.

Measurement of Frontal Midline Theta Oscillations using OPM-MEG (2023)
Journal Article
Rhodes, N., Rea, M., Boto, E., Rier, L., Shah, V., Hill, R. M., …Brookes, M. J. (2023). Measurement of Frontal Midline Theta Oscillations using OPM-MEG. NeuroImage, 271, Article 120024. https://doi.org/10.1016/j.neuroimage.2023.120024

Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over... Read More about Measurement of Frontal Midline Theta Oscillations using OPM-MEG.

Deuterium brain imaging at 7T during D2O dosing (2022)
Journal Article
Cocking, D., Damion, R. A., Franks, H., Jaconelli, M., Wilkinson, D., Brook, M., …Bowtell, R. (2023). Deuterium brain imaging at 7T during D2O dosing. Magnetic Resonance in Medicine, 89(4), 1514-1521. https://doi.org/10.1002/mrm.29539

Purpose To characterize the (2H) deuterium MR signal measured from human brain at 7T in participants loading with D2O to ˜1.5% enrichment over a six-week period. Methods 2H spectroscopy and imaging measurements were used to track the time-course... Read More about Deuterium brain imaging at 7T during D2O dosing.