Outputs (31)

Post-Task Responses following Working Memory and Movement are Driven by Transient Spectral Bursts with Similar Characteristics (2024)
Journal Article
Coleman, S. C., Seedat, Z. A., Pakenham, D. O., Quinn, A. J., Brookes, M. J., Woolrich, M. W., & Mullinger, K. J. (in press). Post-Task Responses following Working Memory and Movement are Driven by Transient Spectral Bursts with Similar Characteristics. Human Brain Mapping,

The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as “post-task responses... Read More about Post-Task Responses following Working Memory and Movement are Driven by Transient Spectral Bursts with Similar Characteristics.

Measurement of Frontal Midline Theta Oscillations using OPM-MEG (2023)
Journal Article
Rhodes, N., Rea, M., Boto, E., Rier, L., Shah, V., Hill, R. M., …Brookes, M. J. (2023). Measurement of Frontal Midline Theta Oscillations using OPM-MEG. NeuroImage, 271, Article 120024. https://doi.org/10.1016/j.neuroimage.2023.120024

Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over... Read More about Measurement of Frontal Midline Theta Oscillations using OPM-MEG.

Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes (2022)
Journal Article
Coleman, S. C., Seedat, Z. A., Whittaker, A. C., Lenartowicz, A., & Mullinger, K. J. (2023). Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes. NeuroImage, 265, Article 119801. https://doi.org/10.1016/j.neuroimage.2022.119801

Post-task responses (PTRs) are transitionary responses occurring for several seconds between the end of a stimulus/task and a period of rest. The most well-studied of these are beta band (13 – 30 Hz) PTRs in motor networks following movement, often c... Read More about Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes.

Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study (2022)
Journal Article
Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., …Gaetz, W. (2022). Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human Brain Mapping, https://doi.org/10.1002/hbm.26118

Epilepsy is a highly heterogeneous neurological disorder with variable etiology, manifestation, and response to treatment. It is imperative that new models of epileptiform brain activity account for this variability, to identify individual needs and... Read More about Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study.

Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control (2022)
Journal Article
Mayhew, S. D., Coleman, S. C., & Mullinger, K. J. (2022). Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control. NeuroImage, 253, Article 119081. https://doi.org/10.1016/j.neuroimage.2022.119081

Ipsilateral sensorimotor (iSM1) cortex negative BOLD responses (NBR) are observed to unilateral tasks and are thought to reflect a functionally relevant component of sensorimotor inhibition. Evidence suggests that sensorimotor inhibitory mechanisms d... Read More about Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control.

Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults (2021)
Journal Article
Burley, C. V., Francis, S. T., Whittaker, A. C., Mullinger, K. J., & Lucas, S. J. E. (2021). Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults. Brain and Behavior, 11(7), Article e02126. https://doi.org/10.1002/brb3.2126

Introduction: Resting cerebral blood flow (CBF) and perfusion measures have been used to determine brain health. Studies showing variation in resting CBF with age and fitness level using different imaging approaches have produced mixed findings. We a... Read More about Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults.

Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals (2021)
Journal Article
Burley, C. V., Francis, S. T., Thomas, K. N., Whittaker, A. C., Lucas, S. J., & Mullinger, K. J. (2021). Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals. Frontiers in Physiology, 12, Article 656746. https://doi.org/10.3389/fphys.2021.656746

Cerebrovascular reactivity (CVR) is used as an outcome measure of brain health. Traditionally, lower CVR is associated with ageing, poor fitness and brain-related conditions (e.g. stroke, dementia). Indeed, CVR is suggested as a biomarker for disease... Read More about Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals.

Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study (2020)
Journal Article
Briley, P. M., Liddle, E. B., Simmonite, M., Jansen, M., White, T. P., Balain, V., …Liddle, P. F. (2021). Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6(12), 1145-1156. https://doi.org/10.1016/j.bpsc.2020.10.018

Background: There is emerging evidence for abnormal beta oscillations in psychosis. Beta oscillations are likely to play a key role in the coordination of sensorimotor information that is crucial to healthy mental function. Growing evidence suggests... Read More about Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study.

The CO2?stimulus duration and steady?state time?point used for data extraction alters the cerebrovascular reactivity outcome measure (2020)
Journal Article
Burley, C. V., Lucas, R. A., Whittaker, A. C., Mullinger, K., & Lucas, S. J. (2020). The CO2?stimulus duration and steady?state time?point used for data extraction alters the cerebrovascular reactivity outcome measure. Experimental Physiology, 105(5), 893-903. https://doi.org/10.1113/ep087883

Cerebrovascular reactivity to carbon dioxide (CVR) is a common functional test to assess brain vascular health, though conflicting age and fitness effects have been reported. Studies have used different CO2 -stimulus durations to induce CVR and extra... Read More about The CO2?stimulus duration and steady?state time?point used for data extraction alters the cerebrovascular reactivity outcome measure.

Alpha/beta power decreases track the fidelity of stimulus-specific information (2019)
Journal Article
Griffiths, B. J., Mayhew, S. D., Mullinger, K. J., Jorge, J., Charest, I., Wimber, M., & Hanslmayr, S. (2019). Alpha/beta power decreases track the fidelity of stimulus-specific information. eLife, 8, https://doi.org/10.7554/elife.49562

© 2019, Griffiths et al. Massed synchronised neuronal firing is detrimental to information processing. When networks of task-irrelevant neurons fire in unison, they mask the signal generated by task-critical neurons. On a macroscopic level, such sync... Read More about Alpha/beta power decreases track the fidelity of stimulus-specific information.