Outputs (354)

Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial (2016)
Journal Article
McIntosh, E., Gray, A., Daniels, J., Gill, S., Ives, N., Jenkinson, C., …on behalf of The PD SURG Collaborators Group. (2016). Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial. Movement Disorders, 31(8), 1173-1182. https://doi.org/10.1002/mds.26423

Introduction Williams and colleagues reported that DBS surgery for patients with advanced PD improves motor function and quality of life compared to best medical therapy alone at 1 year, but with surgery‐related side effects in a minority. This ar... Read More about Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial.

Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD-'Assessing QbTest Utility in ADHD'(AQUA): A randomised controlled trial - December 01, 2014 (2016)
Journal Article
Hall, C. L., Walker, G. M. .., Valentine, A. Z., Guo, B., Kaylor-Hughes, C., James, M., …Hollis, C. (2016). Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD-'Assessing QbTest Utility in ADHD'(AQUA): A randomised controlled trial - December 01, 2014. BMJ Open, 6(1), Article e006838corr2. https://doi.org/10.1136/bmjopen-2014-006838corr2

Guidelines for reporting embedded recruitment trials (2016)
Journal Article
Madurasinghe, V. W., Eldridge, S., & Forbes, G. (in press). Guidelines for reporting embedded recruitment trials. Trials, 17, https://doi.org/10.1186/s13063-015-1126-y

Background: Recruitment to clinical trials is difficult with many trials failing to recruit to target and within time. Embedding trials of recruitment interventions within host trials may provide a successful way to improve this. There are no guidel... Read More about Guidelines for reporting embedded recruitment trials.

A systematic review of interventions to reduce hospitalisation in Parkinson's disease (2016)
Journal Article
Muzerengi, S., Herd, C., Rick, C., & Clarke, C. (2016). A systematic review of interventions to reduce hospitalisation in Parkinson's disease. Parkinsonism and Related Disorders, 24, 3-7. https://doi.org/10.1016/j.parkreldis.2016.01.011

The neurodegenerative process in Parkinson's disease (PD) results in a relentless progression of motor and non-motor symptoms. Affected individuals are frequently hospitalised for complications of the disease including falls, fractures, infections, a... Read More about A systematic review of interventions to reduce hospitalisation in Parkinson's disease.

Measuring asymmetry and testing symmetry (2015)
Journal Article
Partlett, C., & Patil, P. (2017). Measuring asymmetry and testing symmetry. Annals of the Institute of Statistical Mathematics, 69(2), 429-460. doi:10.1007/s10463-015-0547-4

In this paper, we show that some of the most commonly used tests of symmetry do not have power which is reflective of the size of asymmetry. This is because the primary rationale for the test statistics that are proposed in the literature to test for... Read More about Measuring asymmetry and testing symmetry.

The provision of NHS health checks in a community setting: an ethnographic account (2015)
Journal Article
Riley, R., Coghill, N., Montgomery, A., Feder, G., & Horwood, J. (in press). The provision of NHS health checks in a community setting: an ethnographic account. BMC Health Services Research, 15, https://doi.org/10.1186/s12913-015-1209-1

Background: The UK National Health Service Health Checks programme aims to reduce avoidable cardiovascular deaths, disability and health inequalities in England. However, due to the reported lower uptake of screening in specific black and minority et... Read More about The provision of NHS health checks in a community setting: an ethnographic account.

Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: study protocol for a randomised controlled trial (CRAMMS) (2015)
Journal Article
Lincoln, N. B., das Nair, R., Bradshaw, L., Constantinescu, C. S., Drummond, A. E. R., Erven, A., …Morgan, M. (2015). Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: study protocol for a randomised controlled trial (CRAMMS). Trials, 16(1), Article 556. https://doi.org/10.1186/s13063-015-1016-3

Background People with multiple sclerosis have problems with memory and attention. Cognitive rehabilitation is a structured set of therapeutic activities designed to retrain an individual’s memory and other cognitive functions. Cognitive rehabili... Read More about Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: study protocol for a randomised controlled trial (CRAMMS).

Journeying through Dementia, a community-based self-management intervention for people aged 65 years and over: a feasibility study to inform a future trial (2015)
Journal Article
Sprange, K., Mountain, G., Shortland, K., Craig, C., Blackburn, D. J., Bowie, P., …Spencer, M. (2015). Journeying through Dementia, a community-based self-management intervention for people aged 65 years and over: a feasibility study to inform a future trial. Pilot and Feasibility Studies, 1, Article 42. https://doi.org/10.1186/s40814-015-0039-6

Background A study to determine the feasibility of conducting a future population-based trial into a self-management intervention for community-living adults with early stage dementia included evaluation of intervention content and modes of deli... Read More about Journeying through Dementia, a community-based self-management intervention for people aged 65 years and over: a feasibility study to inform a future trial.

Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial (2015)
Journal Article
Costeloe, K., Hardy, P., Juszczak, E., Wilks, M., & Millar, M. R. (2016). Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial. Lancet, 387(10019), 649-660. https://doi.org/10.1016/s0140-6736%2815%2901027-2

© 2016 Elsevier Ltd. Summary Background Probiotics may reduce necrotising enterocolitis and late-onset sepsis after preterm birth. However, there has been concern about the rigour and generalisability of some trials and there is no agreement about wh... Read More about Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial.

Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial (2015)
Journal Article
Robling, M., Bekkers, M., Bell, K., Butler, C. C., Cannings-John, R., Channon, S., …Torgerson, D. (2016). Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial. Lancet, 2016(387), https://doi.org/10.1016/S0140-6736%2815%2900392-X

Background Many countries now offer support to teenage mothers to help them to achieve long-term socioeconomic stability and to give a successful start to their children. The Family Nurse Partnership (FNP) is a licensed intensive home-visiting int... Read More about Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial.