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Outputs (85)

Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey (2021)
Journal Article
Hoedl, M., Eglseer, D., Bernet, N., Everink, I., Gordon, A. L., Lohrmann, C., …Bauer, S. (2022). Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey. Journal of Nursing Scholarship, 54(4), 462-469. https://doi.org/10.1111/jnu.12758

Purpose: Falls are a highly prevalent problem in hospitals and nursing homes with serious negative consequences such as injuries, increased care dependency, or even death. The aim of this study was to provide a comprehensive insight into institution-... Read More about Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey.

Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation (2021)
Journal Article
Logan, P. A., Horne, J. C., Gladman, J. R., Gordon, A. L., Robertson, K., Sach, T., …Sims, E. (2021). Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation. BMJ, 375, Article e066991. https://doi.org/10.1136/bmj-2021-066991

Objectives To determine the clinical and cost effectiveness of a multifactorial fall prevention programme compared with usual care in long term care homes. Design Multicentre, parallel, cluster randomised controlled trial. Setting Long term care home... Read More about Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation.

Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men (2021)
Journal Article
Guo, Y., Piasecki, J., Swiecicka, A., Ireland, A., Phillips, B. E., Atherton, P. J., …Piasecki, M. (2022). Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men. GeroScience, https://doi.org/10.1007/s11357-021-00482-3

Long-term exercise training has been considered as an effective strategy to counteract age-related hormonal declines and minimise muscle atrophy. However, human data relating circulating hormone levels with motor nerve function are scant. The aims of... Read More about Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men.

Metabolomics as an Important Tool for Determining the Mechanisms of Human Skeletal Muscle Deconditioning (2021)
Journal Article
Alldritt, I., Greenhaff, P. L., & Wilkinson, D. J. (2021). Metabolomics as an Important Tool for Determining the Mechanisms of Human Skeletal Muscle Deconditioning. International Journal of Molecular Sciences, 22(24), Article 13575. https://doi.org/10.3390/ijms222413575

Muscle deconditioning impairs both locomotor function and metabolic health, and is associated with reduced quality life and increased mortality rates. Despite an appreciation of the existence of phenomena such as muscle anabolic resistance, mitophagy... Read More about Metabolomics as an Important Tool for Determining the Mechanisms of Human Skeletal Muscle Deconditioning.

Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial (2021)
Journal Article
the TICH-2 Investigators, Law, Z. K., Appleton, J. P., Scutt, P., Roberts, I., Al-Shahi Salman, R., …Sprigg, N. (2021). Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial. Stroke, 53(4), 1141-1148. https://doi.org/10.1161/STROKEAHA.121.035191

Background: Seeking consent rapidly in acute stroke trials is crucial as interventions are time sensitive. We explored the association between consent pathways and time to enrollment in the TICH-2 (Tranexamic Acid in Intracerebral Haemorrhage-2) rand... Read More about Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial.

The importance of protein sources to support muscle anabolism in cancer: An expert group opinion (2021)
Journal Article
Ford, K. L., Arends, J., Atherton, P. J., Engelen, M. P., Gonçalves, T. J., Laviano, A., …Prado, C. M. (2022). The importance of protein sources to support muscle anabolism in cancer: An expert group opinion. Clinical Nutrition, 41(1), 192-201. https://doi.org/10.1016/j.clnu.2021.11.032

This opinion paper presents a short review of the potential impact of protein on muscle anabolism in cancer, which is associated with better patient outcomes. Protein source is a topic of interest for patients and clinicians, partly due to recent emp... Read More about The importance of protein sources to support muscle anabolism in cancer: An expert group opinion.

Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance (2021)
Journal Article
van Haastregt, J. C., Everink, I. H. J., Schols, J. M. G. A., Grund, S., Gordon, A. L., Poot, E. P., …Achterberg, W. P. (2022). Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. European Geriatric Medicine, 13(1), 291-304. https://doi.org/10.1007/s41999-021-00575-4

Purpose: To describe a guidance on the management of post-acute COVID 19 patients in geriatric rehabilitation. Methods: The guidance is based on guidelines for post-acute COVID-19 geriatric rehabilitation developed in the Netherlands, updated with re... Read More about Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance.

Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol (2021)
Preprint / Working Paper
Gladman, J., Aloraibi, S., Greenhaff, P., Piasecki, M., Phillips, B., Atherton, P., …Gordon, A. Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol

East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and... Read More about Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol.

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Preprint / Working Paper
Usman, A., Lewis, S., Clarkson, P., & Gordon, A. Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol

Introduction There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

GPs’ involvement to improve care quality in care homes in the UK: a realist review (2021)
Journal Article
Chadborn, N. H., Devi, R., Williams, C., Sartain, K., Goodman, C., & Gordon, A. L. (2021). GPs’ involvement to improve care quality in care homes in the UK: a realist review. Health Services and Delivery Research, 9(20), 1-76. https://doi.org/10.3310/hsdr09200

Background Organising health-care services for residents living in care homes is an important area of development in the UK and elsewhere. Medical care is provided by general practitioners in the UK, and the unique arrangement of the NHS means that... Read More about GPs’ involvement to improve care quality in care homes in the UK: a realist review.