Skip to main content

Research Repository

Advanced Search

Outputs (6)

Potential nutraceutical properties of leaves from several commonly cultivated plants (2020)
Journal Article
Amat-ur-Rasool, H., Symes, F., Tooth, D., Schaffert, L., Elmorsy, E., Ahmed, M., …Carter, W. G. (2020). Potential nutraceutical properties of leaves from several commonly cultivated plants. Biomolecules, 10(11), 1-22. https://doi.org/10.3390/biom10111556

Chronic dietary ingestion of suitable phytochemicals may assist with limiting or negating neurodegenerative decline. Current therapeutics used to treat Alzheimer disease elicit broad adverse drug reactions, and alternative sources of cholinesterase i... Read More about Potential nutraceutical properties of leaves from several commonly cultivated plants.

A pilot study of alterations in oxidized angiotensinogen and antioxidants in pre-eclamptic pregnancy (2020)
Journal Article
Dahabiyeh, L. A., Tooth, D., Kurlak, L. O., Mistry, H. D., Pipkin, F. B., & Barrett, D. A. (2020). A pilot study of alterations in oxidized angiotensinogen and antioxidants in pre-eclamptic pregnancy. Scientific Reports, 10(1), https://doi.org/10.1038/s41598-020-58930-7

© 2020, The Author(s). The oxidation status of angiotensinogen (AGT) may have a critical role in pre-eclampsia. We used a validated, quantitative, mass spectrometry-based method to measure the oxidized and total AGT levels in plasma of pre-eclamptic... Read More about A pilot study of alterations in oxidized angiotensinogen and antioxidants in pre-eclamptic pregnancy.

Profiling of 54 plasma glycoproteins by label-free targeted LC-MS/MS (2018)
Journal Article
Dahabiyeh, L. A., Tooth, D., & Barrett, D. A. (2019). Profiling of 54 plasma glycoproteins by label-free targeted LC-MS/MS. Analytical Biochemistry, 567, 72-81. https://doi.org/10.1016/j.ab.2018.12.011

Glycoproteins play a central role in diverse biological processes and are linked with many serious human diseases. In this paper we present a simple, reproducible and cost-effective analytical workflow that enables the reliable quantification of clin... Read More about Profiling of 54 plasma glycoproteins by label-free targeted LC-MS/MS.

Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin (2016)
Journal Article
Scott, D., Garner, T. P., Long, J., Strachan, J., Mistry, S. C., Bottrill, A. R., …Layfield, R. (in press). Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin. Proteomics, 16(14), https://doi.org/10.1002/pmic.201600067

Unanchored polyubiquitin chains are emerging as importanregulators of cellular physiology with diverse roles paralleling those of substrate-conjugated polyubiquitin. However tools able to discriminate unanchored polyubiquitin chains of different isop... Read More about Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.

Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport (2014)
Journal Article
Evans, R. D., Robinson, C., Briggs, D. A., Tooth, D. J., Ramalho, J. S., Cantero, M., …Hume, A. N. (2014). Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport. Current Biology, 24(15), 1743-1750. https://doi.org/10.1016/j.cub.2014.06.019

In animal cells, microtubule and actin tracks and their associated motors (dynein, kinesin, and myosin) are thought to regulate long- and short-range transport, respectively [1-8]. Consistent with this, microtubules extend from the perinuclear centro... Read More about Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport.

Alcohol-related brain damage in humans (2014)
Journal Article
Quintas, L. E. M., Erdozain, A. M., Morentin, B., Bedford, L., King, E., Tooth, D., …Carter, W. G. (2014). Alcohol-related brain damage in humans. PLoS ONE, 9(4), Article e93586. https://doi.org/10.1371/journal.pone.0093586

Chronic excessive alcohol intoxications evoke cumulative damage to tissues and organs. We examined prefrontal cortex (Brodmann’s area (BA) 9) from 20 human alcoholics and 20 age, gender, and postmortem delay matched control subjects. H & E staining a... Read More about Alcohol-related brain damage in humans.