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Outputs (95)

Data?driven machine?learning analysis of potential embolic sources in embolic stroke of undetermined source (2020)
Journal Article
Ntaios, G., Weng, S. F., Perlepe, K., Akyea, R., Condon, L., Lambrou, D., …Michel, P. (2021). Data‐driven machine‐learning analysis of potential embolic sources in embolic stroke of undetermined source. European Journal of Neurology, 28(1), 192-201. https://doi.org/10.1111/ene.14524

Background: Hierarchical clustering, a common “unsupervised” machine‐learning algorithm, is advantageous for exploring potential underlying aetiology in particularly heterogeneous diseases. We investigated potential embolic sources in ESUS using a da... Read More about Data?driven machine?learning analysis of potential embolic sources in embolic stroke of undetermined source.

Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus (2020)
Journal Article
Maula, A., Kendrick, D., Kai, J., & Griffiths, F. (2021). Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus. Diabetic Medicine, 38(1), Article e14394. https://doi.org/10.1111/dme.14394

Background: Obesity and diabetes are major public health problems. Current approaches to weight loss show varying success. Complex community‐based interventions work through several interconnected stages. An individual’s actions in response to an int... Read More about Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus.

Understanding pregnant women’s adherence‐related beliefs about Nicotine Replacement Therapy for smoking cessation: A qualitative study (2020)
Journal Article
McDaid, L., Thomson, R., Emery, J., Coleman, T., Cooper, S., Phillips, L., …Naughton, F. (2021). Understanding pregnant women’s adherence‐related beliefs about Nicotine Replacement Therapy for smoking cessation: A qualitative study. British Journal of Health Psychology, 26(1), 179-197. https://doi.org/10.1111/bjhp.12463

Introduction: Reducing smoking during pregnancy is a public health priority. Nicotine Replacement Therapy (NRT) is offered routinely to pregnant women who smoke in the UK. However, evidence of treatment efficacy in this population is weak, most likel... Read More about Understanding pregnant women’s adherence‐related beliefs about Nicotine Replacement Therapy for smoking cessation: A qualitative study.

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people (2020)
Journal Article
Hippisley-Cox, J., Young, D., Coupland, C., Channon, K. M., Tan, P. S., Harrison, D. A., …Watkinson, P. J. (2020). Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people. Heart, 106(19), 1503-1511. https://doi.org/10.1136/heartjnl-2020-317393

Background: There is uncertainty about the associations of angiotensive enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) drugs with COVID-19 disease. We studied whether patients prescribed these drugs had altered risks of contracting sev... Read More about Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people.

Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging (2020)
Journal Article
Sullivan, F. M., Mair, F. S., Anderson, W., Armory, P., Briggs, A., Chew, C., …Schembri, S. (2021). Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging. European Respiratory Journal, 57(1), Article 2000670. https://doi.org/10.1183/13993003.00670-2020

The EarlyCDT-Lung test is a high specificity blood-based autoantibody biomarker that could contribute to predicting lung cancer risk. Here we report on the results of a phase IV biomarker evaluation of whether using the EarlyCDT-Lung test and any sub... Read More about Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging.

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models (2020)
Journal Article
Akyea, R. K., Leonardi-Bee, J., Asselbergs, F. W., Patel, R. S., Durrington, P., Wierzbicki, A. S., …Weng, S. F. (2020). Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models. BMJ Open, 10(7), Article e034564. https://doi.org/10.1136/bmjopen-2019-034564

Introduction: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and increasing life expectancy, more people are surviving initial CVD events. However, models t... Read More about Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models.

Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England (2020)
Journal Article
Persson, M. S., Harman, K. E., Vinogradova, Y., Langan, S. M., Hippisley-Cox, J., Thomas, K. S., & Gran, S. (2020). Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England. BMJ Open, 10(7), e035934. https://doi.org/10.1136/bmjopen-2019-035934

Objectives: The validity of bullous pemphigoid and pemphigus vulgaris recording in routinely collected healthcare data in the UK is unknown. We assessed the positive predictive value (PPV) for bullous pemphigoid and pemphigus vulgaris primary care Re... Read More about Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England.

Is family history still underutilised? Exploring the views and experiences of primary care doctors in Malaysia (2020)
Journal Article
Hussein, N., Malik, T. F. A., Salim, H., Samad, A., Qureshi, N., & Ng, C. J. (2020). Is family history still underutilised? Exploring the views and experiences of primary care doctors in Malaysia. Journal of Community Genetics, 11(4), 413-420. https://doi.org/10.1007/s12687-020-00476-2

Family history has long been recognised as a non-invasive and inexpensive tool to identify individuals at risk of genetic conditions. Even in the era of evolving genetic and genomic technology, the role of family history in predicting individual risk... Read More about Is family history still underutilised? Exploring the views and experiences of primary care doctors in Malaysia.

Healthcare Professionals’ Beliefs, Attitudes, Knowledge, and Behavior Around Vaping in Pregnancy and Postpartum: A Qualitative Study (2020)
Journal Article
Hunter, A., Yargawa, J., Notley, C., Nath, S., Ussher, M., Bobak, A., …Cooper, S. (2021). Healthcare Professionals’ Beliefs, Attitudes, Knowledge, and Behavior Around Vaping in Pregnancy and Postpartum: A Qualitative Study. Nicotine and Tobacco Research, 23(3), 471–478. https://doi.org/10.1093/ntr/ntaa126

Introduction: Finding effective ways to help pregnant women quit smoking and maintain long-term abstinence is a public health priority. Electronic cigarettes (i.e., vaping) could be a suitable cessation tool in pregnancy for those who struggle to qu... Read More about Healthcare Professionals’ Beliefs, Attitudes, Knowledge, and Behavior Around Vaping in Pregnancy and Postpartum: A Qualitative Study.