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Pseudomonas spp. in Canine Otitis Externa (2023)
Journal Article
Secker, B., Shaw, S., & Atterbury, R. J. (2023). Pseudomonas spp. in Canine Otitis Externa. Microorganisms, 11(11), Article 2650. https://doi.org/10.3390/microorganisms11112650

Canine otitis externa (OE) is a commonly diagnosed condition seen in veterinary practice worldwide. In this review, we discuss the mechanisms of the disease, with a particular focus on the biological characteristics of Pseudomonas aeruginosa and the... Read More about Pseudomonas spp. in Canine Otitis Externa.

Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions (2023)
Journal Article
Dlamini, S. B., Gigante, A. M., Hooton, S. P. T., & Atterbury, R. J. (2023). Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions. Microorganisms, 11(10), Article 2389. https://doi.org/10.3390/microorganisms11102389

Salmonella causes a range of diseases in humans and livestock of considerable public health and economic importance. Widespread antimicrobial use, particularly in intensively produced livestock (e.g., poultry and pigs) may contribute to the rise of m... Read More about Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions.

Isolation and Characterization of a Novel Phage Collection against Avian-Pathogenic Escherichia coli (2023)
Journal Article
Nicolas, M., Trotereau, A., Culot, A., Moodley, A., Atterbury, R., Wagemans, J., …Schouler, C. (2023). Isolation and Characterization of a Novel Phage Collection against Avian-Pathogenic Escherichia coli. Microbiology Spectrum, 11(3), Article e04296-22. https://doi.org/10.1128/spectrum.04296-22

The increase in antibiotic-resistant avian-pathogenic Escherichia coli (APEC), the causative agent of colibacillosis in poultry, warrants urgent research and the development of alternative therapies. This study describes the isolation and characteriz... Read More about Isolation and Characterization of a Novel Phage Collection against Avian-Pathogenic Escherichia coli.

Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs (2022)
Journal Article
Thanki, A. M., Mignard, G., Atterbury, R. J., Barrow, P., Millard, A. D., & Clokie, M. R. J. (2022). Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs. Microbiology Spectrum, 10(3), e0042222. https://doi.org/10.1128/spectrum.00422-22

Nontyphoidal Salmonella spp. are a leading cause of human food poisoning and can be transmitted to humans via consuming contaminated pork. To reduce Salmonella spread to the human food chain, bacteriophage (phage) therapy could be used to reduce bact... Read More about Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs.

Predatory bacteria as living antibiotics – where are we now? (2021)
Journal Article
Atterbury, R. J., & Tyson, J. (2021). Predatory bacteria as living antibiotics – where are we now?. Microbiology, 167(1), Article 001025. https://doi.org/10.1099/mic.0.001025

Antimicrobial resistance (AMR) is a global health and economic crisis. With too few antibiotics in development to meet current and anticipated needs, there is a critical need for new therapies to treat Gram-negative infections. One potential approach... Read More about Predatory bacteria as living antibiotics – where are we now?.

Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius (2020)
Journal Article
Brown, H. L., Metters, G., Hitchings, M. D., Wilkinson, T. S., Sousa, L., Cooper, J., …Jenkins, R. (2020). Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius. Applied and Environmental Microbiology, 86(20), Article e01768-20. https://doi.org/10.1128/aem.01768-20

Staphylococcus pseudintermedius causes opportunistic infections in dogs. It also has significant zoonotic potential, with the emergence of multidrug-resistance leading to difficulty treating both animal and human infections. Manuka honey has previous... Read More about Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius.

Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage (2020)
Journal Article
Atterbury, R. J., Gigante, A. M., Rubio Lozano, M. D. L. S., Méndez Medina, R. D., Robinson, G., Alloush, H., …Allen, V. M. (2020). Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage. Virology Journal, 17, Article 98. https://doi.org/10.1186/s12985-020-01368-0

Background: Enteric infections caused by Salmonella spp. remain a major public health burden worldwide. Chickens are known to be a major reservoir for this zoonotic pathogen. The presence of Salmonella in poultry farms and abattoirs is associated wit... Read More about Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage.

An improved cleaning system to reduce microbial contamination of poultry transport crates in the United Kingdom (2020)
Journal Article
Atterbury, R., Gigante, A., Tinker, D., Howell, M., & Allen, V. (2020). An improved cleaning system to reduce microbial contamination of poultry transport crates in the United Kingdom. Journal of Applied Microbiology, 128(6), 1776-1784. https://doi.org/10.1111/jam.14576

© 2020 The Society for Applied Microbiology Aim: Following previous research on improving the cleaning of crates used to transport broiler chickens from the farm to the abattoir, a demonstration project was undertaken to investigate improvements in c... Read More about An improved cleaning system to reduce microbial contamination of poultry transport crates in the United Kingdom.

Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot (2020)
Journal Article
Hobley, L., Summers, J. K., Till, R., Milner, D. S., Atterbury, R. J., Stroud, A., …Sockett, R. E. (2020). Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot. Journal of Bacteriology, 202(6), Article e00629-19. https://doi.org/10.1128/JB.00629-19

Copyright © 2020 Hobley et al. Bacteria are preyed upon by diverse microbial predators, including bacteriophage and predatory bacteria, such as Bdellovibrio bacteriovorus. While bacteriophage are used as antimicrobial therapies in Eastern Europe and... Read More about Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot.

Veterinary use of bacteriophage therapy in intensively-reared livestock (2019)
Journal Article
Gigante, A., & Atterbury, R. J. (2019). Veterinary use of bacteriophage therapy in intensively-reared livestock. Virology Journal, 16(1), https://doi.org/10.1186/s12985-019-1260-3

Zoonoses are infectious diseases transmitted directly or indirectly between animals and humans. Several important zoonotic pathogens colonize farm animals asymptomatically, which may lead to contamination of the food chain and public health hazards.... Read More about Veterinary use of bacteriophage therapy in intensively-reared livestock.

Sex pilus specific bateriophage to drive bacterial population towards antibiotic sensitivity (2019)
Journal Article
Colom, J., Batista, D., Baig, A., Tang, Y., Liu, S., Yuan, F., …Barrow, P. (2019). Sex pilus specific bateriophage to drive bacterial population towards antibiotic sensitivity. Scientific Reports, 9, 1-11. https://doi.org/10.1038/s41598-019-48483-9

Antimicrobial resistance (AMR) is now a major global problem largely resulting from the overuse of antibiotics in humans and livestock. In some AMR bacteria, resistance is encoded by conjugative plasmids expressing sex-pili that can readily spread re... Read More about Sex pilus specific bateriophage to drive bacterial population towards antibiotic sensitivity.

Reviving Phage Therapy for the Treatment of Cholera (2018)
Journal Article
Bhandare, S., Colom, J., Baig, A., Ritchie, J. M., Bokhari, H., Shah, M. A., …Atterbury, R. J. (2019). Reviving Phage Therapy for the Treatment of Cholera. Journal of Infectious Diseases, 219(5), 786-794. https://doi.org/10.1093/infdis/jiy563

Cholera remains a major risk in developing countries, particularly after natural or man-made disasters. Vibrio cholerae El Tor is the most important cause of these outbreaks, and is becoming increasingly resistant to antibiotics, so alternative thera... Read More about Reviving Phage Therapy for the Treatment of Cholera.

Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal (2018)
Journal Article
Sarkar, B., Sarkar, S., Das, M., Bhowmick, T., Koley, H., Atterbury, R., & Chakrabarti, A. (2018). Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal. Journal of Global Infectious Diseases, 10(2), https://doi.org/10.4103/jgid.jgid_37_17

Objectives: We have isolated a total of five newer cholera phages which are novel broad host range to incorporate with the existing phage typing schemes for an extended typing scheme. Materials and Methods: These newly isolated phages were well chara... Read More about Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal.

Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China (2017)
Journal Article
Bhandare, S. G., Warry, A., Emes, R. D., Su, J., Barrow, P. A., & Atterbury, R. J. (2017). Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China. Genome Announcements, 5(47), Article e01019-17. https://doi.org/10.1128/genomeA.01019-17

The complete genome sequences of seven closely related Vibrio cholerae phages isolated from environmental sites in southeastern China are reported here. Phages QH, CJY, H1, H2, H3, J2, and J3 are members of the Podoviridae family and are highly simil... Read More about Complete Genome Sequences of Seven Vibrio cholerae Phages Isolated in China.

Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29 (2017)
Journal Article
Bhandare, S. G., Warry, A., Emes, R. D., Hooton, S. P., Barrow, P. A., & Atterbury, R. J. (2017). Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29. Genome Announcements, 5(46), Article e01013. https://doi.org/10.1128/genomeA.01013-17

The complete genomes of two Vibrio cholerae bacteriophages of potential interest for cholera bacteriophage (phage) therapy were sequenced and annotated. The genome size of phage 24 is 44,395 bp encoding 71 putative proteins, and that of phage X29 is... Read More about Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29.

Biology and genomics of an historic therapeutic Escherichia coli bacteriophage collection (2017)
Journal Article
Baig, A., Colom, J., Barrow, P., Schouler, C., Moodley, A., Lavigne, R., & Atterbury, R. J. (2017). Biology and genomics of an historic therapeutic Escherichia coli bacteriophage collection. Frontiers in Microbiology, 8, Article 1652. https://doi.org/10.3389/fmicb.2017.01652

We have performed microbiological and genomic characterization of an historic collection of nine bacteriophages, specifically infecting a K1 E. coli O18:K1:H7 ColV+ strain. These phages were isolated from sewage and tested for their efficacy in vivo... Read More about Biology and genomics of an historic therapeutic Escherichia coli bacteriophage collection.

Molecular epidemiology of nontyphoidal Salmonella in poultry and poultry products in India: implications for human health (2015)
Journal Article
Saravanan, S., Purushothaman, V., Murthy, T. R. G., Sukumar, K., Srinivasan, P., Gowthaman, V., …Kuchipudi, S. V. (2015). Molecular epidemiology of nontyphoidal Salmonella in poultry and poultry products in India: implications for human health. Indian Journal of Microbiology, 55(3), https://doi.org/10.1007/s12088-015-0530-z

Human infections with non-typhoidal Salmonella (NTS) serovars are increasingly becoming a threat to human health globally. While all motile Salmonellae have zoonotic potential, Salmonella Enteritidis and Salmonella Typhimurium are most commonly assoc... Read More about Molecular epidemiology of nontyphoidal Salmonella in poultry and poultry products in India: implications for human health.

Investigation into the animal species contents of popular wet pet foods (2015)
Journal Article
Maine, I. R., Atterbury, R. J., & Chang, K. (2015). Investigation into the animal species contents of popular wet pet foods. Acta Veterinaria Scandinavica, 57(1), https://doi.org/10.1186/s13028-015-0097-z

Background: The use of the generic term “meat and animal derivatives” in declared ingredient lists of pet foods in the European Union is virtually universal. In the wake of the 2013 “horse meat scandal” in the human food chain, we examined the presen... Read More about Investigation into the animal species contents of popular wet pet foods.

Fleas and smaller fleas: virotherapy for parasite infections (2013)
Journal Article
Hyman, P., Atterbury, R. J., & Barrow, P. (2013). Fleas and smaller fleas: virotherapy for parasite infections. Trends in Microbiology, 21(5), https://doi.org/10.1016/j.tim.2013.02.006

Bacteriophages are viruses of bacteria that are used for controlling bacterial food-borne pathogens and have been proposed for more extensive usage in infection control. Protists are now recognised to harbour viruses and virus-like particles. We prop... Read More about Fleas and smaller fleas: virotherapy for parasite infections.

Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria (2012)
Journal Article
Hobley, L., Lerner, T. R., Williams, L. E., Lambert, C., Till, R., Milner, D. S., …Sockett, R. E. (2012). Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria. BMC Genomics, 13(670), https://doi.org/10.1186/1471-2164-13-670

Background: Evolution equipped Bdellovibrio bacteriovorus predatory bacteria to invade other bacteria, digesting and replicating, sealed within them thus preventing nutrient-sharing with organisms in the surrounding environment. Bdellovibrio were... Read More about Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria.