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Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity (2020)
Journal Article
Gascoyne, L. E., Brookes, M. J., Rathnaiah, M., Zia Ul Haq Katshu, M., Koelewijn, L., Williams, G., …Morris, P. G. (2021). Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity. NeuroImage: Clinical, 29, Article 102524. https://doi.org/10.1016/j.nicl.2020.102524

Magnetoencephalography (MEG) measures magnetic fields generated by synchronised neural current flow and provides direct inference on brain electrophysiology and connectivity, with high spatial and temporal resolution. The movement-related beta decrea... Read More about Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity.

Quantifying the core deficit in classical schizophrenia (2020)
Journal Article
Rathnaiah, M., Liddle, E., Gascoyne, L., Kumar, J., Zia Ul Haq Katshu, M., Faruqi, C., …Liddle, P. F. (2020). Quantifying the core deficit in classical schizophrenia. Schizophrenia Bulletin Open, 1(1), Article sgaa031. https://doi.org/10.1093/schizbullopen/sgaa031

In the classical descriptions of schizophrenia, Kraepelin and Bleuler recognised disorganization and impoverishment of mental activity as fundamental symptoms. Their classical descriptions also included a tendency to persisting disability. The psycho... Read More about Quantifying the core deficit in classical schizophrenia.

Changes in electrophysiological markers of cognitive control after administration of galantamine (2018)
Journal Article
Robson, S. E., Gascoyne, L. E., Mullinger, K. J., Robson, S., Kumar, J., O'Neill, G. C., …Liddle, P. F. (2018). Changes in electrophysiological markers of cognitive control after administration of galantamine. NeuroImage: Clinical, 20, 228-235. https://doi.org/10.1016/j.nicl.2018.07.019

© 2018 The healthy brain is able to maintain a stable balance between bottom-up sensory processing and top-down cognitive control. The neurotransmitter acetylcholine plays a substantial role in this. Disruption of this balance could contribute to sym... Read More about Changes in electrophysiological markers of cognitive control after administration of galantamine.

Glutathione and glutamate in schizophrenia: a 7T MRS study (2018)
Journal Article
Kumar, J., Liddle, E. B., Fernandes, C. C., Palaniyappan, L., Hall, E. L., Robson, S. E., …Liddle, P. F. (2018). Glutathione and glutamate in schizophrenia: a 7T MRS study. Molecular Psychiatry, 25(4), 873–882. https://doi.org/10.1038/s41380-018-0104-7

© 2018 The Author(s) In schizophrenia, abnormal neural metabolite concentrations may arise from cortical damage following neuroinflammatory processes implicated in acute episodes. Inflammation is associated with increased glutamate, whereas the antio... Read More about Glutathione and glutamate in schizophrenia: a 7T MRS study.

Abnormal visuomotor processing in schizophrenia (2015)
Journal Article
Robson, S. E., Brookes, M. J., Hall, E. L., Palaniyappan, L., Kumar, J., Skelton, M., …Morris, P. G. (2016). Abnormal visuomotor processing in schizophrenia. NeuroImage: Clinical, 12, 869-878. https://doi.org/10.1016/j.nicl.2015.08.005

Subtle disturbances of visual and motor function are known features of schizophrenia and can greatly impact quality of life; however, few studies investigate these abnormalities using simple visuomotor stimuli. In healthy people, electrophysiological... Read More about Abnormal visuomotor processing in schizophrenia.