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A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Priority Setting Partnership (2022)
Journal Article
Grindlay, D. J. C., Davis, T. R. C., Kennedy, D., Larson, D., Furniss, D., Cowan, K., …Karantana, A. (2022). A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Priority Setting Partnership. BMC Medical Research Methodology, 22(1), Article 292. https://doi.org/10.1186/s12874-022-01777-5

Background: To report our recommended methodology for extracting and then confirming research uncertainties – areas where research has failed to answer a research question – derived from previously published literature during a broad scope Priority S... Read More about A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Priority Setting Partnership.

The global incidence of bullous pemphigoid: a systematic review and meta-analysis (2021)
Journal Article
Persson, M. S., Begum, N., Grainge, M. J., Harman, K. E., Grindlay, D., & Gran, S. (2022). The global incidence of bullous pemphigoid: a systematic review and meta-analysis. British Journal of Dermatology, 186(3), 414-425. https://doi.org/10.1111/bjd.20743

Background: Bullous pemphigoid (BP) is an autoimmune blistering disorder that mainly affects older people. Although the disease is associated with considerable morbidity and mortality, the burden of disease worldwide is unclear. Objectives: The study... Read More about The global incidence of bullous pemphigoid: a systematic review and meta-analysis.

Safety of topical corticosteroids in atopic eczema: an umbrella review (2021)
Journal Article
Axon, E., Chalmers, J. R., Santer, M., Ridd, M. J., Lawton, S., Langan, S. M., …Thomas, K. S. (2021). Safety of topical corticosteroids in atopic eczema: an umbrella review. BMJ Open, 11(7), Article e046476. https://doi.org/10.1136/bmjopen-2020-046476

Objective An umbrella review summarising all safety data from systematic reviews of topical corticosteroids (TCS) in adults and children with atopic eczema. Methods Embase, MEDLINE, PubMed, Cochrane Database of Systematic Reviews and the Centre of Ev... Read More about Safety of topical corticosteroids in atopic eczema: an umbrella review.

Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base (2021)
Journal Article
Tasker, F., Kirby, L., Grindlay, D. J. C., Lewis, F., & Simpson, R. C. (2021). Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base. Skin Health and Disease, 1(3), Article e52. https://doi.org/10.1002/ski2.52

Background Lichen sclerosus (LS) is a chronic, inflammatory dermatosis. Initial treatment with superpotent topical corticosteroids is the accepted and evidence-based first-line therapy. For those who do not respond after exclusion of other potenti... Read More about Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base.

Measurement properties of patient?reported outcome measures for eczema control: a systematic review (2021)
Journal Article
Stuart, B., Howells, L., Pattinson, R., Chalmers, J., Grindlay, D., Rogers, N., …Thomas, K. (2021). Measurement properties of patient‐reported outcome measures for eczema control: a systematic review. Journal of the European Academy of Dermatology and Venereology, 35(10), 1987-1993. https://doi.org/10.1111/jdv.17335

Atopic eczema (herein referred to as ‘eczema’) is a skin disease characterized by remitting and relapsing symptoms. The Harmonising Outcome Measures for Eczema (HOME) initiative was developed to establish a core outcome set (COS) for eczema to be mea... Read More about Measurement properties of patient?reported outcome measures for eczema control: a systematic review.

Can atopic eczema and psoriasis coexist? A systematic review and meta?analysis (2021)
Journal Article
Cunliffe, A., Gran, S., Ali, U., Grindlay, D., Lax, S., Williams, H., & Burden-Teh, E. (2021). Can atopic eczema and psoriasis coexist? A systematic review and meta?analysis. Skin Health and Disease, 1(2), Article e29. https://doi.org/10.1002/ski2.29

Importance: Previous studies report both co-existence and mutual exclusivity of atopic eczema (AE) and psoriasis, but these have not been appraised systematically. Knowledge of such disease association throws light on disease mechanisms and may influ... Read More about Can atopic eczema and psoriasis coexist? A systematic review and meta?analysis.

Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback (2021)
Journal Article
Sellers, E., Baillie, S., Dean, R., Warman, S., Janicke, H., Arlt, S. P., …Verheyen, K. (2021). Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback. Veterinary Evidence, 6(1), 1-17. https://doi.org/10.18849/ve.v6i1.392

‘EBVM Learning’ is a freely available resource created in 2015 by an international team with the support of RCVS Knowledge. The resource comprises a series of online modules teaching the fundamental concepts of evidence-based veterinary medicine (EBV... Read More about Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback.

Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review (2021)
Journal Article
Deshmukh, S. R., Mousoulis, C., Marson, B. A., Grindlay, D., Karantana, A., the Core Outcome Set for Hand Fractures and Joint Injuries in Adults Group, …Montgomery, A. A. (2021). Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review. Journal of Hand Surgery (European Volume), 46(5), 488-495. https://doi.org/10.1177/1753193420983719

© The Author(s) 2021. This study identifies the treatment outcome domains used in recently published studies on the treatment of hand fractures and joint injuries with the aim to inform development of a core outcome set. Seven databases were searched... Read More about Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review.

A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults (2020)
Journal Article
Taha, R. H. M., Grindlay, D., Deshmukh, S., Montgomery, A., Davis, T. R. C., & Karanatana, A. (2022). A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults. Hand, 17(5), 869-878. https://doi.org/10.1177/1558944720974363

Metacarpal shaft fractures are common hand injuries that predominantly affect younger patients. There is wide variability in their treatment with no consensus on best practice. We performed a systematic review to assess the breadth and quality of ava... Read More about A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults.

Critically Appraised Topics (CATs) in Veterinary Medicine: Applying Evidence in Clinical Practice (2020)
Journal Article
Brennan, M. L., Arlt, S. P., Belshaw, Z., Buckley, L., Corah, L., Doit, H., …White, C. (2020). Critically Appraised Topics (CATs) in Veterinary Medicine: Applying Evidence in Clinical Practice. Frontiers in Veterinary Science, 7, Article 314. https://doi.org/10.3389/fvets.2020.00314

Critically appraised topics (CATs) are evidence syntheses that provide veterinary professionals with information to rapidly address clinical questions and support the practice of evidence-based veterinary medicine (EBVM). They also have an important... Read More about Critically Appraised Topics (CATs) in Veterinary Medicine: Applying Evidence in Clinical Practice.

L-carnitine supplementation in non-alcoholic fatty liver disease: A systematic review and meta-analysis (2020)
Journal Article
Thiagarajan, P., Chalmers, J., Ban, L., Grindlay, D., & Aithal, G. P. (2020). L-carnitine supplementation in non-alcoholic fatty liver disease: A systematic review and meta-analysis. World Journal of Meta-Analysis, 8(1), 4-14. https://doi.org/10.13105/wjma.v8.i1.4

BACKGROUND Non-alcoholic fatty liver disease (NAFLD) dominates the landscape of modern hepatology. Affecting 25% of the general population, there is critical unmet need to identify broadly available, safe and cost-effective treatments. Cumulative ev... Read More about L-carnitine supplementation in non-alcoholic fatty liver disease: A systematic review and meta-analysis.

Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials (2019)
Journal Article
Mousoulis, C., Thomas, K., Leighton, P., Deshmukh, S., Grindlay, D., & Karantana, A. (2020). Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials. Journal of Hand Surgery (European Volume), 45(2), 111-118. https://doi.org/10.1177/1753193419865897

The aim of this study was to identify and assess all existing randomized studies on treatment interventions for hand fractures and joint injuries, to inform practice and plan future research. PubMed, Cochrane CENTRAL, MEDLINE and Embase were searche... Read More about Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials.

A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis (2019)
Journal Article
Patel, M., Lee, S. I., Akyea, R. K., Grindlay, D., Francis, N., Levell, N. J., …Thomas, K. (2019). A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis. British Journal of Dermatology, 181(6), 1156-1165. https://doi.org/10.1111/bjd.17857

Background: Cellulitis can be a difficult diagnosis to make. 31% of patients admitted from the emergency department with suspected lower limb cellulitis are misdiagnoses, with incorrect treatment potentially resulting in avoidable hospital admission... Read More about A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis.

What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 3: nomenclature and outcome assessment (2019)
Journal Article
Lloyd-Lavery, A., Solman, L., Grindlay, D. J. C., Rogers, N. K., Thomas, K. S., & Harman, K. E. (2019). What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 3: nomenclature and outcome assessment. Clinical and Experimental Dermatology, 44(4), 376-380. https://doi.org/10.1111/ced.13886

© 2019 British Association of Dermatologists This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It presents the key findings from 11 systematic reviews published in 2016 that focus on AE outc... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 3: nomenclature and outcome assessment.

What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 2: Epidemiology, aetiology and risk factors (2019)
Journal Article
Lloyd-Lavery, A., Solman, L., Grindlay, D. J. C., Rogers, N. K., Thomas, K. S., & Harman, K. E. (2019). What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 2: Epidemiology, aetiology and risk factors. Clinical and Experimental Dermatology, 44(4), 370-375. https://doi.org/10.1111/ced.13853

© 2019 British Association of Dermatologists This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It presents the key findings from 14 sy... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 2: Epidemiology, aetiology and risk factors.

What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention (2019)
Journal Article
Solman, L., Lloyd-Lavery, A., Grindlay, D. J. C., Rogers, N. K., Thomas, K. S., & Harman, K. E. (2019). What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention. Clinical and Experimental Dermatology, 44(4), 363-369. https://doi.org/10.1111/ced.13885

© 2019 British Association of Dermatologists This review is part of a series of annual updates summarizing the evidence base for atopic eczema (AE). It provides a summary of key findings from 28 systematic reviews that were published or indexed durin... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention.

Open Versus Arthroscopic Repair of 1B Ulnar-Sided Triangular Fibrocartilage Complex Tears: A Systematic Review (2019)
Journal Article
Robba, V., Fowler, A., Karantana, A., Grindlay, D., & Lindau, T. (2020). Open Versus Arthroscopic Repair of 1B Ulnar-Sided Triangular Fibrocartilage Complex Tears: A Systematic Review. Hand, 15(4), 456-464 . https://doi.org/10.1177/1558944718815244

Background: Peripheral 1B tears of the triangular fibrocartilage complex (TFCC) can result in distal radioulnar joint (DRUJ) instability. In the context of associated DRUJ instability, combined evidence supports successful outcomes for peripheral tea... Read More about Open Versus Arthroscopic Repair of 1B Ulnar-Sided Triangular Fibrocartilage Complex Tears: A Systematic Review.

Registration and outcome reporting bias in randomised controlled trials of distal radius fracture treatment: a systematic review (2018)
Journal Article
Lee, S., Khan, T., Grindlay, D., & Karantana, A. (2018). Registration and outcome reporting bias in randomised controlled trials of distal radius fracture treatment: a systematic review. JBJS Open Access, 24(3), Article e0065. https://doi.org/10.2106/JBJS.OA.17.00065

Background: The aim was to systematically evaluate the completeness of trial registration and the extent of outcome-reporting bias in modern randomised controlled trials (RCTs) of distal radius fracture treatment. This is the first study to investiga... Read More about Registration and outcome reporting bias in randomised controlled trials of distal radius fracture treatment: a systematic review.