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All Outputs (22)

Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial (2022)
Journal Article
Hancox, J., Ayling, K., Bedford, L., Vedhara, K., Robertson, J. F. R., Young, B., …Kendrick., D. (2023). Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial. Journal of Public Health, 45(2), e275–e284. https://doi.org/10.1093/pubmed/fdac032

Background: The Early CDT®-Lung antibody blood test plus serial CT-scans for test-positives reduces late-stage lung cancer presentation. This study assessed psychological outcomes of this approach. Methods: Randomised controlled trial (n=12,208) c... Read More about Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial.

Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis (2021)
Journal Article
Leonardi-Bee, J., Boateng, C., Faria, R., Eliman, K., Young, B., & Qureshi, N. (2021). Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis. Atherosclerosis, 338, 7-14. https://doi.org/10.1016/j.atherosclerosis.2021.09.014

Background and aims: Cascade testing in relatives of index cases is the most cost-effective approach to identifying people with familial hypercholesterolemia (FH); however, it is currently unclear which strategy to contact relatives would be the most... Read More about Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis.

Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study (2020)
Journal Article
Young, B., Fogarty, A. W., Skelly, R., Shaw, D., Sturrock, N., Norwood, M., …Cranwell, J. (2020). Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study. BMC Medical Informatics and Decision Making, 20(1), 80. https://doi.org/10.1186/s12911-020-1087-2

BACKGROUND: Avoidable use of diagnostic tests can both harm patients and increase the cost of healthcare. Nudge-type educational interventions have potential to modify clinician behaviour while respecting clinical autonomy and responsibility, but the... Read More about Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study.

Developing logic models to inform public health policy outcome evaluation: an example from tobacco control (2020)
Journal Article
Langley, T., Gillespie, D., Lewis, S., Eminson, K., Brennan, A., Docherty, G., & Young, B. (2020). Developing logic models to inform public health policy outcome evaluation: an example from tobacco control. Journal of Public Health, 43(3), 639-646. https://doi.org/10.1093/pubmed/fdaa032

Background The evaluation of large-scale public health policy interventions often relies on observational designs where attributing causality is challenging. Logic models – visual representations of an intervention’s anticipated causal pathway –... Read More about Developing logic models to inform public health policy outcome evaluation: an example from tobacco control.

Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study (2019)
Journal Article
Young, B., Cranwell, J., Fogarty, A. W., Skelly, R., Sturrock, N., Norwood, M., …Thurley, P. (2019). Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study. BMC Health Services Research, 19, https://doi.org/10.1186/s12913-019-4712-y

Background: In the context of increasing availability of computed tomography (CT) scans, judicious use of ionising radiation is a priority to minimise the risk of future health problems. Hence, education of clinicians on the risks and benefits of CT... Read More about Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study.

Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study (2019)
Journal Article
Lewis, S., Young, B., Thurley, P., Shaw, D., Cranwell, J., Skelly, R., …Fogarty, A. W. (2019). Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study. Future Healthcare Journal, 6(3), 204-208. https://doi.org/10.7861/fhj.2019-0001

Background: Behavioural insights or ‘nudge’ theory suggests that non-directional interventions may be used to modify human behaviour. We have tested the hypothesis that the provision of the cost of common blood tests with their results may modify sub... Read More about Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study.

Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT) (2019)
Journal Article
Young, B., Bedford, L., das Nair, R., Gallant, S., Littleford, R., Robertson, J. F., …ECLS Study Team. (2020). Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT). Journal of Evaluation in Clinical Practice, 26(3), 893-902. https://doi.org/10.1111/jep.13230

Rationale, aims, and objectives: High response rates to research questionnaires can help to ensure results are more representative of the population studied and provide increased statistical power, on which the study may have been predicated. Improvi... Read More about Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT).

Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study (2019)
Journal Article
Lewis, S., Shaw, D., Langley, T., Fogarty, A., Young, B., & Cranwell, O. (2019). Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study. Clinical Medicine, 19(4), 290-293. https://doi.org/10.7861/clinmedicine.19-4-290

Computerised tomography (CT) is readily available in developed countries. As one of the side-effects includes an increased risk of cancer, interventions that may encourage more judicious use of CT scans are important. Behavioural economics theory inc... Read More about Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study.

Determinants of motivation to quit in smokers screened for the early detection of lung cancer: a qualitative study (2018)
Journal Article
Young, B., Vedhara, K., Kendrick, D., Littleford, R., Robertson, J. F. R., Sullivan, F. M., …in collaboration with the ECLS study team. (2018). Determinants of motivation to quit in smokers screened for the early detection of lung cancer: a qualitative study. BMC Public Health, 18(1), Article 1276. https://doi.org/10.1186/s12889-018-6211-1

Background: The promotion of smoking cessation within lung cancer screening could lead to benefits for smoking-related disease and improve cost-effectiveness of screening. Little is known about how smokers respond to lung cancer screening and how thi... Read More about Determinants of motivation to quit in smokers screened for the early detection of lung cancer: a qualitative study.

Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours? (2018)
Journal Article
Clark, M. E., Young, B., Bedford, L. E., Robertson, J. F., das Nair, R., Vedhara, K., …Kendrick, D. (2019). Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?. Journal of Public Health, 41(3), 600-608. https://doi.org/10.1093/pubmed/fdy158

Background Lung cancer screening can reduce lung cancer mortality by 20%. Screen-detected abnormalities may provide teachable moments for smoking cessation. This study assesses impact of pulmonary nodule detection on smoking behaviours within the fi... Read More about Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?.

Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules (2018)
Journal Article
Clark, M. E., Bedford, L. E., Young, B., Robertson, J. F., das Nair, R., Vedhara, K., …Kendrick, D. (2018). Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules. Lung Cancer, 124, 160-167. https://doi.org/10.1016/j.lungcan.2018.08.001

Objectives: To determine the psychological response (thoughts, perceptions and affect) to a diagnosis of pulmonary nodules following a novel antibody blood test and computed tomography (CT) scans within a UK population. Materials and methods: This... Read More about Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules.

Effectiveness of mass media campaigns to reduce alcohol consumption and harm: a systematic review (2018)
Journal Article
Young, B., Lewis, S., Katikireddi, S. V., Bauld, L., Stead, M., Angus, K., …Langley, T. (2018). Effectiveness of mass media campaigns to reduce alcohol consumption and harm: a systematic review. Alcohol and Alcoholism, 53(1), https://doi.org/10.1093/alcalc/agx094

Aims: To assess the effectiveness of mass media messages to reduce alcohol consumption and related harms using a systematic literature review. Methods: Eight databases were searched along with reference lists of eligible studies. Studies of any desi... Read More about Effectiveness of mass media campaigns to reduce alcohol consumption and harm: a systematic review.

OP36 Decisions about smoking in patients screened with the early cdt-lung test for the early detection of lung cancer: a qualitative study (2017)
Journal Article
Young, B., Vedhara, K., Robertson, J., & das Nair, R. (in press). OP36 Decisions about smoking in patients screened with the early cdt-lung test for the early detection of lung cancer: a qualitative study. Journal of Epidemiology and Community Health, 71(Supp 1), Article A19. https://doi.org/10.1136/jech-2017-SSMAbstracts.36

Background: Routine screening for lung cancer in high risk groups (characterised by age and smoking history) is recommended in the USA and may be implemented elsewhere. It is unclear whether being screened for lung cancer promotes smoking cessation... Read More about OP36 Decisions about smoking in patients screened with the early cdt-lung test for the early detection of lung cancer: a qualitative study.

Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives (2017)
Journal Article
Kendrick, D., Ablewhite, J., Achana, F., Benford, P., Clacy, R., Coffey, F., …Zou, K. (2017). Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives. Programme Grants for Applied Research, 5(14), https://doi.org/10.3310/pgfar05140

Background: Unintentional injuries among 0- to 4-year-olds are a major public health problem incurring substantial NHS, individual and societal costs. However, evidence on the effectiveness and cost-effectiveness of preventative interventions is lack... Read More about Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives.

Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research (2017)
Journal Article
Young, B., Bedford, L., Kendrick, D., Vedhara, K., Robertson, J., & das Nair, R. (in press). Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research. Journal of Public Health, https://doi.org/10.1093/pubmed/fdx026

Background: This review aimed to better understand experiences of being invited to cancer screening and associated decision-making. Methods: Qualitative evidence explaining UK cancer screening attendance decisions was systematically identified. Data... Read More about Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research.

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial (2017)
Journal Article
Sullivan, F., Farmer, E., Mair, F. S., Treweek, S., Kendrick, D., Jackson, C., …Schembri, S. (2017). Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial. BMC Cancer, 17(1), https://doi.org/10.1186/s12885-017-3175-y

Background: Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cell surface proteins in the ear... Read More about Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial.