Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI

Sadykhov, E.G.; Pirogov, Yu.A.; Anisimov, N.V.; Gulyaev, M.V.; Pavlovskaya, Galina; Meersmann, T.; Belyaev, V.N.; Fomina, D.V.

Abstract

Sodium is a key element in a living organism. The increase of its concentration is an indicator of many pathological conditions. 23Na magnetic resonance imaging (MRI) is a quantitative method that allows to determine the sodium content in tissues and organs in vivo. This method has not yet entered clinical practice widely, but it has already been used as a clinical research tool to investigate diseases such as brain tumors, breast cancer, stroke, multiple sclerosis, hypertension, diabetes, ischemic heart disease, osteoarthritis. The active development of the 23Na MRI is promoted by the growth of available magnetic fields, the expansion of hardware capabilities, and the development of pulse sequences with ultra-short echo time.

Citation

Sadykhov, E., Pirogov, Y., Anisimov, N., Gulyaev, M., Pavlovskaya, G., Meersmann, T., …Fomina, D. (2018). Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI. Applied Magnetic Resonance, 925-957. https://doi.org/10.1007/s00723-018-1045-7

• Journal Article Type: Review
• Acceptance Date: Jul 27, 2018
• Online Publication Date: Jul 27, 2018
• Publication Date: Sep 17, 2018
• Deposit Date: Jan 31, 2019
• Publicly Available Date: Jul 28, 2019
• Print ISSN: 0937-9347
• Electronic ISSN: 1613-7507
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Issue: 49
• Article Number: 9
• Pages: 925-957
• DOI: https://doi.org/10.1007/s00723-018-1045-7
• Public URL: https://nottingham-repository.worktribe.com/output/974656
• Publisher URL: https://link.springer.com/article/10.1007/s00723-018-1045-7
• Contract Date: Jan 31, 2019