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Outputs (39)

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA (2021)
Journal Article
Wang, Y., Meng, X., Wang, A., Xie, X., Pan, Y., Johnston, S. C., …CHANCE-2 Investigators. (2021). Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA. New England Journal of Medicine, 385(27), 2520-2530. https://doi.org/10.1056/NEJMoa2111749

BACKGROUND Comparisons between ticagrelor and clopidogrel for the secondary prevention of stroke in CYP2C19 loss-of-function carriers have not been extensively performed. METHODS We conducted a randomized, double-blind, placebo-controlled trial at 20... Read More about Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA.

Physical Activity Interventions After Hip or Knee Joint Replacement: a Systematic Review (2020)
Journal Article
Ishaku, T., Min, S. M., & Hall, M. (2020). Physical Activity Interventions After Hip or Knee Joint Replacement: a Systematic Review. Current Physical Medicine and Rehabilitation Reports, 8(3), 299-311. https://doi.org/10.1007/s40141-020-00275-3

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Purpose of Review: This study is aimed at describing and evaluating physical activity interventions in individuals that have undergone hip or knee joint replacement due to osteoar... Read More about Physical Activity Interventions After Hip or Knee Joint Replacement: a Systematic Review.

Prospective analysis of health-related quality of life after surgery for spinal metastases (2020)
Journal Article
Quraishi, N. A., Pasku, D., Koch, J. E. J., Arealis, G., Boszczyk, B. M., & Edwards, K. L. (2020). Prospective analysis of health-related quality of life after surgery for spinal metastases. European Spine Journal, https://doi.org/10.1007/s00586-020-06396-6

Purpose Most spinal metastases are detected late and thus the impact of treatment on the health related quality of life (HRQOL) is an important consideration. This study investigated the HRQOL following surgery for spinal metastases. Methods Prospect... Read More about Prospective analysis of health-related quality of life after surgery for spinal metastases.

Natural course of adult-onset vitelliform lesions in eyes with and without comorbid subretinal drusenoid deposits (2020)
Journal Article
Yeung, A. M., Wilde, C., Awad, M., Giannouladis, K., Lakshmanan, A., Dua, H., & Amoaku, W. M. (2020). Natural course of adult-onset vitelliform lesions in eyes with and without comorbid subretinal drusenoid deposits. International Ophthalmology, 40, 1501–1508. https://doi.org/10.1007/s10792-020-01319-2

Purpose Adult vitelliform lesions (AVL) are associated with age related macular degeneration (AMD) and subretinal drusenoid deposits (SRDD). We evaluated the natural course of AVL, assessing the influence of SRDD on disease progression, visual fun... Read More about Natural course of adult-onset vitelliform lesions in eyes with and without comorbid subretinal drusenoid deposits.

Access to and interventions to improve maternity care services for immigrant women: a narrative synthesis systematic review (2020)
Journal Article
Higginbottom, G. M., Evans, C., Morgan, M., Bharj, K. K., Eldridge, J., Hussain, B., & Salt, K. (2020). Access to and interventions to improve maternity care services for immigrant women: a narrative synthesis systematic review. Health Services and Delivery Research, 8(14), 1-122. https://doi.org/10.3310/hsdr08140

Limited evidence suggests experiences of immigrant women accessing and using UK maternity services were mixed but largely poor, and there were few rigorously evaluated interventions focused on improving care.

Clinical Scene Segmentation with Tiny Datasets (2019)
Conference Proceeding
Smith, T. J., Sharkey, D., Crowe, J., & Valstar, M. (2019). Clinical Scene Segmentation with Tiny Datasets. In 2019 IEEE/CVF International Conference on Computer Vision Workshop (ICCVW) (1637-1645). https://doi.org/10.1109/ICCVW.2019.00203

Many clinical procedures could benefit from automatic scene segmentation and subsequent action recognition. Using Convolutional Neural Networks to semantically segment meaningful parts of an image or video is still an unsolved problem. This becomes e... Read More about Clinical Scene Segmentation with Tiny Datasets.

Specialist healthcare services for UK care home residents: a latent class analysis (2019)
Journal Article
Hargreaves, C., Tucker, S., Hughes, J., Hays, R., & Challis, D. (2019). Specialist healthcare services for UK care home residents: a latent class analysis. Primary Health Care Research and Development, 20, Article e132. https://doi.org/10.1017/s1463423619000586

Aim: To identify discrete approaches to specialist healthcare support for older care home residents in the UK and to estimate their prevalence. Background: Internationally, a range of new initiatives are emerging to meet the multiple and complex heal... Read More about Specialist healthcare services for UK care home residents: a latent class analysis.

Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis (2019)
Journal Article
Rowbotham, N. J., Smith, S. J., Elliott, Z. C., Leighton, P. A., Rayner, O. C., Morley, R., & Smyth, A. R. (2019). Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis. Research Involvement and Engagement, 5(1), Article 24. https://doi.org/10.1186/s40900-019-0159-x

Background The James Lind Alliance (JLA) method is well recognised for setting research priorities. The JLA approach involves a combination of surveys and workshop interactions between patients, carers and health care professionals to identify and... Read More about Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis.

The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases (2019)
Journal Article
Pander, B., Harris, G., Scott, D. J., Winzer, K., Köpke, M., Simpson, S. D., …Henstra, A. M. (2019). The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases. Applied Microbiology and Biotechnology, 103(17), 7275-7286. https://doi.org/10.1007/s00253-019-10015-w

Carbonic anhydrase catalyses the interconversion of carbon dioxide and water to bicarbonate and protons. It was unknown if the industrial relevant acetogen Clostridium autoethanogenum possesses these enzymes. We identified two putative carbonic anhyd... Read More about The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases.