@article { , title = {The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study}, abstract = {To understand how children and young people with tic disorders were affected by COVID-19, we compared pre and during pandemic scores on the Yale Global Tic Severity Scale (YGTSS). Participants were young people (N = 112; male:78\%; 9–17 years) randomised to the control arm of the “ORBIT-Trial” (ISRCTN70758207, ClinicalTrials.gov-NCT03483493). For this analysis, the control arm was split into two groups: one group was followed up to 12-months’ post-randomisation before the pandemic started (pre-COVID group, n = 44); the other group was impacted by the pandemic at the 12-month follow-up (during-COVID group, n = 47). Mixed effects linear regression modelling was conducted to explore differences in YGTSS at 6- and 12-months post-randomisation. There were no significant differences in tic symptom or severity between participants who were assessed before and during COVID-19. This finding was not influenced by age, gender, symptoms of anxiety or autism spectrum disorder. Thus, the COVID-19 pandemic did not significantly impact existing tic symptoms.}, doi = {10.1007/s10578-022-01348-1}, eissn = {1573-3327}, issn = {0009-398X}, journal = {Child Psychiatry and Human Development}, note = {ORCID Source: CrossrefPath: /0000-0002-5412-6165/work/111725172}, pages = {1499–1509}, publicationstatus = {Published}, publisher = {Springer Science and Business Media LLC}, url = {https://nottingham-repository.worktribe.com/output/7611257}, volume = {54}, keyword = {Psychiatry and Mental health, Developmental and Educational Psychology, Pediatrics, Perinatology and Child Health}, year = {2022}, author = {Hall, Charlotte L. and Marston, Louise and Khan, Kareem and Brown, Beverley J and Sanderson, Charlotte and Andrén, Per and Bennett, Sophie and Heyman, Isobel and Mataix-Cols, David and Serlachius, Eva and Hollis, Chris and Murphy, Tara} }