@article { , title = {Impact of capsaicin on aroma release: in vitro and in vivo analysis}, abstract = {© 2020 The Authors Capsaicin is the main bioactive compound in chili pepper that leads to the perception of “spiciness”. However, the effect of capsaicin on aroma release in the nose remains unexplained. This is the first study designed to measure capsaicin's impact on aroma release during consumption. In vitro studies, using static headspace analysis by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS), showed no impact of capsaicin (5 ppm) on the gas-liquid partitioning equilibria of a range of aroma compounds. However, a significant reduction in aroma release was observed in vivo, during oral melting of a model ice cube system (p < 0.05) included 5 ppm capsaicin. The total release of aroma into the nasal cavity was decreased, such that only 49\% of 3-methylbutanal, 60\% of 1-octen-3-ol and 83\% of linalool was released. This is the first evidence of capsaicin's reduction effect on aroma release during consumption. It was also found that 5 ppm capsaicin increased saliva secretion by 75\%, which may have led to the dilution of aroma compounds in the mouth and directly impacted the aroma release into the nasal cavity. The most hydrophilic compound (3-methylbutanal) was affected by capsaicin to a greater extent than the hydrophobic compound (linalool), the solvent effect of the additional saliva may explain this.}, doi = {10.1016/j.foodres.2020.109197}, eissn = {1873-7145}, issn = {0963-9969}, journal = {Food Research International}, note = {For OA. When final version available change open access type to gold and replace AAM with published version. KJB 02.04.20}, publicationstatus = {Published}, publisher = {Elsevier}, url = {https://nottingham-repository.worktribe.com/output/4242229}, volume = {133}, keyword = {Food science, Chili, Spicy food, Aroma release, Saliva, APCI-MS, Breath analysis}, year = {2020}, author = {Galves, Cassia and Yang, Ni and Racioni Goncalves, Ana Carolina and Chen, Jianshe and Fisk, Ian} }