@article { , title = {Glycemic, Gastrointestinal, Hormonal and Appetitive Responses to Pearl Millet or Oats Porridge Breakfasts: a Randomized, Crossover Trial in Healthy Humans}, abstract = {Whole grain cereal breakfast consumption has been associated with beneficial effects on glucose and insulin metabolism as well as satiety. Pearl millet is a popular ancient grain variety that can be grown in hot, dry regions. However, little is known about its health effects. This study investigated the effect of a pearl millet porridge (PMP) compared with a well-known Scottish oats porridge (SOP) on glycaemic, gastrointestinal, hormonal and appetitive responses. In a randomized, two way crossover trial, 26 healthy participants consumed two iso-energetic/volumetric PMP or SOP breakfast meals, served with a drink of water. Blood samples for glucose, insulin, GLP-1, GIP and PYY, gastric volumes and appetite ratings were collected for two hours postprandially, followed by an ad libitum meal and food intake records for the remainder of the day. The incremental area under the curve (iAUC2h) for blood glucose was not significantly different between the porridges (p ? 0.05). The iAUC2h gastric volume was larger for PMP compared with SOP (p = 0.045). The iAUC2h GIP concentration was significantly lower for PMP compared with SOP (p = 0.001). Other hormones and appetite responses were similar between meals. In conclusion, this study reports, for the first time, data on glycaemic and physiological responses to a pearl millet breakfast, showing that this ancient grain could represent a sustainable, alternative, with health-promoting characteristics comparable to oats. GIP is an incretin hormone linked to triacylglycerol absorption in adipose tissue, therefore the lower GIP response for PMP may be an added health benefit.}, doi = {10.1017/S0007114519001880}, eissn = {1475-2662}, issn = {0007-1145}, journal = {British Journal of Nutrition}, publicationstatus = {Published}, publisher = {Cambridge University Press (CUP)}, url = {https://nottingham-repository.worktribe.com/output/2394744}, keyword = {Bio/Medical/Health - Physiology, Global Research Theme - Health and Wellbeing, Beacon - Precision Imaging, Breakfast porridges, cereal grains, blood glucose, gastric emptying, magnetic resonance imaging, appetite}, year = {2019}, author = {Alyami, Jaber and Whitehouse, Ella and Yakubov, Gleb E and Pritchard, Susan E and Hoad, Caroline L and Blackshaw, Elaine and Heissam, Khaled and Cordon, Sally M and Bligh, H Frances J and Spiller, Robin C and Macdonald, Ian A and Aithal, Guruprasad P and Gowland, Penny A and Taylor, Moira A and Marciani, Luca} }