@article { , title = {A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up}, abstract = {Background Long-term analysis of a randomised trial in Nottingham comparing tamoxifen versus surgery as initial treatment demonstrated that in oestrogen receptor (ER)-unselected cases, surgery achieved better local control, with no difference in overall survival. It was suggested that for patients with ER-rich tumours, local control and survival may be comparable. We now present long-term follow-up of a randomised trial designed to address this clinical scenario. Patients and methods One hundred and fifty three fit elderly (?70 years) women with clinically node-negative primary invasive breast carcinoma}, doi = {10.1093/annonc/mdr630}, eissn = {1569-8041}, issn = {0923-7534}, issue = {9}, journal = {Annals of Oncology}, pages = {2296-2300}, publicationstatus = {Published}, publisher = {Oxford University Press}, url = {https://nottingham-repository.worktribe.com/output/1138781}, volume = {23}, year = {2012}, author = {Johnston, S. J. and Kenny, F. S. and Syed, B. M. and Robertson, J. F. R. and Pinder, S. E. and Winterbottom, L. and Ellis, I. O. and Blamey, R. W. and Cheung, K. L.} }